ArticleWellcome open research2018
Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control study.
Article in Wellcome open research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 71 citations in OpenAlex.
- GDF15 Is Elevated in Conditions of Glucocorticoid Deficiency and Is Modulated by Glucocorticoid Replacement.The Journal of clinical endocrinology and metabolism · 2020Trial
- Pregnancy-related disorders: molecular mechanisms and management.Molecular biomedicine · 2026Review
- Hyperemesis gravidarum revisited: from GDF15 biology to precision multimodal therapy.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- The inverse association between circulatory placental biomarkers in early pregnancy and maternal body mass index.Placenta · 2026Article
- Mitochondrial health, prenatal distress, and gestational age: investigation of cf-mtDNA and GDF15 in two pregnancy studies from the USA and Turkey.Mitochondrion · 2025Article
- Metabolic Messenger: growth differentiation factor 15.Nature metabolism · 2025Review
- Elevated plasma GDF15 combined with FGF21 suggests mitochondrial dysfunction in a subgroup of anorexia nervosa patients.Translational psychiatry · 2025Article
- Sensitivity to fetal hormone GDF15 drives maternal risk of nausea and vomiting during pregnancy.Chinese medical journal · 2025Article
- Central mechanisms of emesis: A role for GDF15.Neurogastroenterology and motility · 2025Review
- Electroacupuncture and vagus nerve stimulation are emerging therapies for hyperemesis gravidarum management.Frontiers in neurology · 2025Review
- Proximate and ultimate causes of pregnancy sickness.Evolution, medicine, and public health · 2025Review
- Health implications of racial differences in serum growth differentiation factor levels among men with obesity.Physiological reports · 2024Article
- GDF15 Knockout Does Not Substantially Impact Perinatal Body Weight or Neonatal Outcomes in Mice.Endocrinology · 2024Article
- Nausea and vomiting in pregnancy (NVP) in Chinese pregnant women: a cross-sectional study.BMC pregnancy and childbirth · 2024Article
- GDF15 knockout does not substantially impact perinatal body weight or neonatal outcomes in mice.bioRxiv : the preprint server for biology · 2024Article
- Molecular pathways in placental-fetal development and disruption.Molecular and cellular endocrinology · 2024Review
- Article
- Nausea, vomiting and conflict in pregnancy: The adaptive significance of Growth-Differentiation Factor 15.Evolution, medicine, and public health · 2024Article
- Insufficient GDF15 expression predisposes women to unexplained recurrent pregnancy loss by impairing extravillous trophoblast invasion.Cell proliferation · 2023Article
- Novel Insights into the Physiology of Nutrient Sensing and Gut-Brain Communication in Surgical and Experimental Obesity Therapy.Obesity surgery · 2023Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 4 countries.
Funding
Abstract
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.