Evidence map›Paper›PMID 30345292›Full record

ArticleInternational journal of genomics2018

Mutations in Homocysteine Metabolism Genes Increase Keratin

Kamila Borowczyk, Jacek Wróblewski, Joanna Suliburska, Noriyuki Akahoshi, Isao Ishii, Hieronim Jakubowski

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Kamila BorowczykDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers-New Jersey Medical School, International Center for Public Health, Newark, NJ 07103, USA.ORCID 0000-0002-8737-7913
Jacek WróblewskiInstitute of Bioorganic Chemistry, 71-704 Poznań, Poland.
Joanna SuliburskaInstitute of Human Nutrition and Dietetics, Poznań University of Life Sciences, 60-632 Poznań, Poland.
Noriyuki AkahoshiDepartment of Health Chemistry, Showa Pharmaceutical University, Tokyo 194-8543, Japan.
Isao IshiiDepartment of Health Chemistry, Showa Pharmaceutical University, Tokyo 194-8543, Japan.ORCID 0000-0002-5367-205X
Hieronim JakubowskiDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers-New Jersey Medical School, International Center for Public Health, Newark, NJ 07103, USA.ORCID 0000-0001-5845-4409
Rutgers, The State University of New Jersey · USShowa Pharmaceutical University · JPInstitute of Bioorganic Chemistry, Polish Academy of Sciences · PLUniversity of Life Sciences in Poznań · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic or nutritional deficiencies in homocysteine (Hcy) metabolism increase Hcy-thiolactone, which causes protein damage by forming isopetide bonds with lysine residues, generating

Identifiers

PMID30345292
PMCPMC6174792
OpenAlexW2892716089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.