Evidence map›Paper›PMID 30345260›Full record

ArticleCanadian journal of gastroenterology & hepatology2018

Characteristics and Changes over Time of Alcohol-Related Chronic Liver Diseases in Italy.

Tommaso Stroffolini, Evangelista Sagnelli, Caterina Sagnelli, Filomena Morisco, Sergio Babudieri, Caterina Furlan, Mario Pirisi, Maurizio Russello, Antonina Smedile, Mariantonietta Pisaturo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Tommaso StroffoliniDepartment of Tropical and Infectious Diseases, Policlinico Umberto I, Rome, Italy.
Evangelista SagnelliDepartment of Mental Health and Public Medicine, Campania University Luigi Vanvitelli, Naples, Italy.
Caterina SagnelliDepartment of Mental Health and Public Medicine, Campania University Luigi Vanvitelli, Naples, Italy.ORCID 0000-0002-6413-7810
Filomena MoriscoDepartment of Clinical Medicine and Surgery, Gastroenterology Unit, University of Naples "Federico II", Naples, Italy.ORCID 0000-0002-9059-8311
Sergio BabudieriClinic of Infectious Diseases, University of Sassari, Sassari, Italy.
Caterina FurlanDepartment of Tropical and Infectious Diseases, Policlinico Umberto I, Rome, Italy.
Mario PirisiDepartment of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.
Maurizio RusselloLiver Unit, Hospital "G. Garibaldi" Catania, Catania, Italy.
Antonina SmedileDepartment of Medical Sciences, University of Turin, Turin, Italy.
Mariantonietta PisaturoUnit of Infectious Diseases, S. Anna and S. Sebastian Hospital, Caserta, Italy.
Piero Luigi AlmasioBiomedical Department of Internal Medicine e Specialities (Di.Bi.M.I.S.), University of Palermo, Palermo, Italy.ORCID 0000-0003-0406-8494
Policlinico Umberto I · ITUniversity of Campania "Luigi Vanvitelli" · ITOspedale Garibaldi · ITOspedale Sant'Anna · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Naples Federico II · ITUniversity of Palermo · ITUniversity of Sassari · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: To evaluate the characteristics of alcohol-related chronic liver disease (CLD) in Italy and their potential changes over time. Patients and Methods: Subjects with CLD were enrolled in two national surveys performed in 2001 and in 2014 in Italy. The two surveys prospectively recruited patients aged ≥ 18 years referring to more than 80 Italian liver units scattered all over the country using similar clinical approach, analytical methods, and threshold of risky alcohol intake definition (≥ 3 units/day in men and ≥ 2 units/day in women). Results: Out of 12,256 enrolled subjects, 2,717 (22.2%) reported a risky alcohol intake. Of them, anti-HCV positive was observed in 48.3% of subjects. The overall sex ratio (M/F) was 3.1, decreasing from 3.8 in 2001 to 1.3 in 2014. Women were significantly older than men (58.9 versus 53.1 years; Conclusions: Risky alcohol intake plays a role in more than one-fifth of CLD in Italy, with a shift over time towards an older age and a more severe liver disease stage. These data put alcohol back in the spotlight with an important role in CLD in the years to come in Italy.

Indexed as

AdultAgedAlcohol DrinkingAlcoholismChronic DiseaseFemaleHealth Risk BehaviorsHealth SurveysHepatitis C AntibodiesHepatitis C, ChronicHumansItalyLiver CirrhosisLiver Diseases, AlcoholicMaleMiddle AgedHepatitis C Antibodies

Identifiers

PMID30345260
PMCPMC6174739
OpenAlexW2892490548

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.