Evidence map›Paper›PMID 30345257›Full record

ArticleFrontiers in cellular and infection microbiology2018

CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in

Joseph D Lykins, Ekaterina V Filippova, Andrei S Halavaty, George Minasov, Ying Zhou, Ievgeniia Dubrovska, Kristin J Flores, Ludmilla A Shuvalova, Jiapeng Ruan, Kamal El Bissati and 14 more

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. FromiScience · 2024
    Article
  2. Article
  3. Article
  4. Review
  5. Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies.Frontiers in cellular and infection microbiology · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Joseph D LykinsPritzker School of Medicine, University of Chicago, Chicago, IL, United States.
Ekaterina V FilippovaCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Andrei S HalavatyCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
George MinasovCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Ying ZhouDepartment of Ophthalmology and Visual Sciences, University of Chicago, Chicago, IL, United States.
Ievgeniia DubrovskaCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Kristin J FloresCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Ludmilla A ShuvalovaCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Jiapeng RuanCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Kamal El BissatiDepartment of Ophthalmology and Visual Sciences, University of Chicago, Chicago, IL, United States.
Sarah DovginIllinois Math and Science Academy, Aurora, IL, United States.
Craig W RobertsStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Stuart WoodsStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Jon D MoultonGene Tools, LLC, Philomath, OR, United States.
Hong MoultonDepartment of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, OR, United States.
Martin J McPhillieDepartment of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom.
Stephen P MuenchSchool of Biomedical Sciences, Faculty of Biological Sciences, and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
Colin W G FishwickSchool of Chemistry and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.
Elisabetta SabiniCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Dhanasekaran ShanmugamBiochemical Sciences Division, CSIR National Chemical Laboratory, Pune, India.
David S RoosDepartment of Biology, University of Pennsylvania, Philadelphia, PA, United States.
Rima McLeodDepartment of Ophthalmology and Visual Sciences, University of Chicago, Chicago, IL, United States.
Wayne F AndersonCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Huân M NgôCenter for Structural Genomics of Infectious Diseases and the Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.

Funding

Short Term Training: Health Professional StudentsT35DK062719 · NIDDK · UNIVERSITY OF CHICAGO · PI CHANG, EUGENE B · 2003 to 2017
$2.9M
NIAID NIH HHS HHSN272200700058CNIAID NIH HHS HHSN272201200026CNIAID NIH HHS HHSN272201700060CNIDDK NIH HHS T35 DK062719
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Crystallography, X-RayEnzymesGene Knockdown TechniquesModels, MolecularProtein ConformationProtozoan ProteinsToxoplasmaEnzymesProtozoan Proteinscrystallographynucleoside diphoshate kinaseornithine aminotransferasephosphoglycerate mutasePPMOribose-5-phosphate isomeraseribulose-3-phosphate epimeraseToxoplasma gondii

Identifiers

PMID30345257
PMCPMC6182094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.