ArticleCritical care research and practice2018
Outcome in Patients with Isolated Moderate to Severe Traumatic Brain Injury.
Article in Critical care research and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Early Tracheostomy versus Late Tracheostomy in Patients with Moderate-to-Severe Traumatic Brain Injury.Asian journal of neurosurgery · 2024Article
- Survival and predictive factors of clinical outcome in patients with severe acquired brain injury.European journal of physical and rehabilitation medicine · 2024Article
- Clinical outcomes and end-of-life treatment in 596 patients with isolated traumatic brain injury: a retrospective comparison of two Dutch level-I trauma centers.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Prevalence of the Minimally Conscious State Among Institutionalized Patients in the Netherlands: A Nationwide Study.Neurology · 2023Article
- The Characteristics of Withdrawal or Withholding of Life-Sustaining Treatment in Severe Traumatic Brain Injury: A Single Japanese Institutional Study.World neurosurgery: X · 2023Article
- Polytrauma patients with severe cervical spine injuries are different than with severe TBI despite similar AIS scores.Scientific reports · 2022Article
- Severe isolated injuries have a high impact on resource use and mortality: a Dutch nationwide observational study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Observational
- Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Incidence of emergency neurosurgical TBI procedures: a population-based study.BMC emergency medicine · 2022Article
- Incidence, causes and consequences of moderate and severe traumatic brain injury as determined by Abbreviated Injury Score in the Netherlands.Scientific reports · 2021Article
- Subspace Clustering of Physiological Data From Acute Traumatic Brain Injury Patients: Retrospective Analysis Based on the PROTECT III Trial.JMIR biomedical engineering · 2021Article
- Traumatic brain injury-the effects of patient age on treatment intensity and mortality.BMC neurology · 2020Article
- The role of serum Dickkopf-1 in predicting 30-day death in severe traumatic brain injury.Brain and behavior · 2020Article
- The evolution of trauma care in the Netherlands over 20 years.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020Review
- Pattern and Outcome of Pediatric Traumatic Brain Injury at Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia: Observational Cross-Sectional Study.Emergency medicine international · 2020Article
- Factors influencing withdrawal of life-sustaining treatments in patients with severe acquired brain injuries: a scoping review.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTraumatic brain injury (TBI) remains a major cause of death. Withdrawal of life-sustaining treatment (WLST) can be initiated if there is little anticipated chance of recovery to an acceptable quality of life. The aim of this study was firstly to investigate WLST rates in patients with moderate to severe isolated TBI and secondly to assess outcome data in the survivor group. MATERIAL AND
methodsA retrospective cohort study was performed. Patients aged ≥ 18 years with moderate or severe isolated TBI admitted to the ICU of a single academic hospital between 2011 and 2015 were included. Exclusion criteria were isolated spinal cord injury and referrals to and from other hospitals. Gathered data included demographics, mortality, cause of death, WLST, and Glasgow Outcome Scale (GOS) score after three months. Good functional outcome was defined as GOS > 3.
resultsOf 367 patients, 179 patients were included after applying inclusion and exclusion criteria. 55 died during admission (33%), of whom 45 (82%) after WLST. Patients undergoing WLST were older, had worse neurological performance at presentation, and had more radiological abnormalities than patients without WLST. The decision to withdraw life-sustaining treatment was made on the day of admission in 40% of patients. In 33% of these patients, this decision was made while the patient was in the Emergency Department. 71% of survivors had a good functional outcome after three months. No patient left hospital with an unresponsive wakefulness syndrome (UWS) or suffered from UWS after three months. One patient died within three months of discharge.
conclusionIn-hospital mortality in isolated brain injured patients was 33%. The vast majority died after a decision to withdraw life-sustaining treatment. None of the patients were discharged with an unresponsive wakefulness syndrome.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.