Evidence map›Paper›PMID 30345064›Full record

ArticleCanadian journal of kidney health and disease2018

Updated Canadian Expert Consensus on Assessing Risk of Disease Progression and Pharmacological Management of Autosomal Dominant Polycystic Kidney Disease.

Steven Soroka, Ahsan Alam, Micheli Bevilacqua, Louis-Philippe Girard, Paul Komenda, Rolf Loertscher, Philip McFarlane, Sanjaya Pandeya, Paul Tam, Daniel G Bichet

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Assessing Risk of Progression in ADPKD.Clinical journal of the American Society of Nephrology : CJASN · 2022
    Article
  11. Article
  12. Patients with Protein-TruncatingClinical journal of the American Society of Nephrology : CJASN · 2021
    Article
  13. Article
  14. Radiographic Imaging in Autosomal Dominant Polycystic Kidney Disease: A Claims Analysis.International journal of nephrology and renovascular disease · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 1 country.

Steven SorokaDivision of Nephrology, Dalhousie University, Halifax, NS, Canada.
Ahsan AlamDivision of Nephrology, Royal Victoria Hospital, McGill University, Montréal, QC, Canada.
Micheli BevilacquaDivision of Nephrology, The University of British Columbia, Vancouver, Canada.
Louis-Philippe GirardDivision of Nephrology, Foothills Medical Centre, University of Calgary, AB, Canada.
Paul KomendaDivision of Nephrology, Seven Oaks General Hospital, University of Manitoba, Winnipeg, Canada.
Rolf LoertscherDivision of Nephrology, Lakeshore General Hospital, McGill University, Pointe-Claire, QC, Canada.
Philip McFarlaneDivision of Nephrology, St. Michael's Hospital, University of Toronto, ON, Canada.
Sanjaya PandeyaDivision of Nephrology, Halton Healthcare, Oakville, ON, Canada.
Paul TamDivision of Nephrology, Scarborough and Rouge Hospital, ON, Canada.
Daniel G BichetDivision of Nephrology, Département de Médecine, Pharmacologie et Physiologie, Hôpital du Sacré-Cœur de Montréal, Université de Montréal, QC, Canada.
Dalhousie University · CAFoothills Medical Centre · CAHalTech · CAHôpital du Sacré-Cœur de Montréal · CALakeshore General Hospital · CARoyal Victoria Hospital · CASt. Michael's Hospital · CAThe Scarborough Hospital · CAUniversity of British Columbia · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this article is to update the previously published consensus recommendations from March 2017 discussing the optimal management of adult patients with autosomal dominant polycystic kidney disease (ADPKD). This document focuses on recent developments in genetic testing, renal imaging, assessment of risk regarding disease progression, and pharmacological treatment options for ADPKD. SOURCES OF INFORMATION: Published literature was searched in PubMed, the Cochrane Library, and Google Scholar to identify the latest evidence related to the treatment and management of ADPKD.

methodsAll pertinent articles were reviewed by the authors to determine if a new recommendation was required, or if the previous recommendation needed updating. The consensus recommendations were developed by the authors based on discussion and review of the evidence. KEY

findingsThe genetics of ADPKD are becoming more complex with the identification of new and rarer genetic variants such as LIMITATIONS: Available literature was limited to English language publications and to publications indexed in PubMed, the Cochrane Library, and Google Scholar. IMPLICATIONS: Advances in the assessment of the risk of disease progression include the validation of the Mayo Clinic Classification for patients with class 1 ADPKD. Advances in the pharmacological management of ADPKD include the expansion of the use of ADH receptor antagonism in patients 18 to 55 years of age with eGFR of 25 to 65 mL/min/1.73 m

Indexed as

ADPKD (autosomal dominant polycystic kidney disease)Canadian consensusdisease progressionkidneyrisk

Identifiers

PMID30345064
PMCPMC6187423
OpenAlexW2897355601

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.