Evidence map›Paper›PMID 30344984›Full record

ArticleHematology reports2018

Human hemoglobin G-Makassar variant masquerading as sickle cell anemia.

Ahmad Sabry Mohamad, Roszymah Hamzah, Veena Selvaratnam, Subramanian Yegapan, Jameela Sathar

Abstract read
In one paragraph

Article in Hematology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Introducing a hemoglobin G-Makassar variant in HSCs by in vivo base editing treats sickle cell disease in mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  3. Article
  4. Article
  5. Genetic therapies for the first molecular disease.The Journal of clinical investigation · 2021
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmad Sabry MohamadUniversiti Kuala Lumpur - British Malaysian Institute, Gombak, Selangor.
Roszymah HamzahHematology Department, Ampang Hospital, Ampang, Selangor, Malaysia.
Veena SelvaratnamHematology Department, Ampang Hospital, Ampang, Selangor, Malaysia.
Subramanian YegapanHematology Department, Ampang Hospital, Ampang, Selangor, Malaysia.
Jameela SatharHematology Department, Ampang Hospital, Ampang, Selangor, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human hemoglobin of G-Makassar variant has been reported very rarely with Beta Thalassemia. In year 1969 Hb GMakassar was first identified in Makassar, Sulawesi (Celebes), Republic of Indonesia. The disease was first published in 1969 and 33 years later it has been reported at a family of Thailand origin. We report a 45-yearold Malay man who was investigated for anemia and thrombocytopenia then diagnosed with Hb G-Makassar. This finding describes as a new Hemoglobin GMakassar discovered in Malaysia after 14 years diagnosed in Thailand.

Indexed as

beta thalassemiaDNA analysiselectrophoresisHemoglobin G-Makassarsickle cell disease

Identifiers

PMID30344984
PMCPMC6176384

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.