Evidence map›Paper›PMID 30344963›Full record

ArticleNeurology international2018

Clinical outcomes of intravenous levetiracetam treatment in patients with renal impairment.

Anyamanee Lapmag, Sunee Lertsinudom, Aporanee Chaiyakam, Kittisak Sawanyawisuth, Somsak Tiamkao, Group on behalf of Integrated Epilepsy Research University Khon Kaen

Open access · goldAbstract read
In one paragraph

Article in Neurology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anyamanee LapmagCinical Pharmacy Division, Faculty of Pharmaceutical Sciences, Khon Kaen University.
Sunee LertsinudomCinical Pharmacy Division, Faculty of Pharmaceutical Sciences, Khon Kaen University.
Aporanee ChaiyakamCinical Pharmacy Division, Faculty of Pharmaceutical Sciences, Khon Kaen University.
Kittisak SawanyawisuthDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Thailand.
Somsak TiamkaoIntegrated Epilepsy Research Group, Khon Kaen University.
Group on behalf of Integrated Epilepsy Research University Khon Kaen
Khon Kaen University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravenous levetiracetam has been approved for use as an antiepileptic drug, as well as in cases of status epilepticus. There are few reports that detail the clinical data and outcomes associated with this antiepileptic drug, particularly in patients with renal impairment. This was a retrospective analytical study conducted at Khon Kaen University's Srinagarind Hospital in Thailand. The study period was between January 1, 2010 and December 31, 2014. The inclusion criteria were that patents were over 15 years old, had renal impairment, and had received intravenous levetiracetam treatment. The main clinical outcomes were seizure control and mortality. Clinical outcomes were compared between those with and without status epilepticus. Mortality of patients with status epilepticus were compared in terms of seizure control and order of intravenous levetiracetam treatment. During the study period, there were 247 patients who met the study criteria. The average age of the patients was 58 years with nearly equal sex distribution. Of those, 90 patients (36.4%) had GRFs of less than 15 mL/min/1.73 m

Indexed as

dosemortalitystatus epilepticus

Identifiers

PMID30344963
PMCPMC6176471
OpenAlexW2897885293

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.