Evidence map›Paper›PMID 30344928›Full record

ArticleOncotarget2018

Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis.

Benjamin Marx, Martin Hufbauer, Paola Zigrino, Slawomir Majewski, Birgid Markiefka, Timo Sachsenheimer, Britta Brügger, Baki Akgül

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Benjamin MarxInstitute of Virology, University of Cologne, Cologne, Germany.
Martin HufbauerInstitute of Virology, University of Cologne, Cologne, Germany.
Paola ZigrinoDepartment of Dermatology and Venereology, University Hospital Cologne, Cologne, Germany.
Slawomir MajewskiDepartment of Dermatology and Venereology, Medical University of Warsaw, Warsaw, Poland.
Birgid MarkiefkaInstitute of Pathology, University Hospital Cologne, Cologne, Germany.
Timo SachsenheimerHeidelberg University Biochemistry Center (BZH), Heidelberg, Germany.
Britta BrüggerHeidelberg University Biochemistry Center (BZH), Heidelberg, Germany.
Baki AkgülInstitute of Virology, University of Cologne, Cologne, Germany.
University of Cologne · DEHeidelberg University · DEUniversity Hospital Cologne · DEMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phospholipids regulate numerous cellular functions and their deregulation is known to be associated with cancer development. Here, we show for the first time that expression of the E6 oncoprotein of human papillomavirus type 8 (HPV8) leads to a profound increase in nuclear phosphatidylinositol-4,5-bisphosphate (PI(4,5)P

Indexed as

E6 oncoproteinhuman papillomavirusnuclear phosphatidylinositol-4,5-bisphosphatephosphatidylinositidesskin cancer

Identifiers

PMID30344928
PMCPMC6183346
OpenAlexW2893891067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.