Evidence map›Paper›PMID 30344797›Full record

ArticleDisease markers2018

Preserved miR-361-3p Expression Is an Independent Prognostic Indicator of Favorable Survival in Cervical Cancer.

Shikai Liu, Lili Song, Hairong Yao, Liang Zhang, Dongkui Xu, Qian Li, Ying Li

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. The functional role of circular RNAs in the pathogenesis of retinoblastoma: a new potential biomarker and therapeutic target?Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shikai LiuDepartment of Obstetrics & Gynecology, Cangzhou Central Hospital, Hebei 061001, China.
Lili SongDepartment of Obstetrics & Gynecology, Cangzhou Central Hospital, Hebei 061001, China.ORCID 0000-0002-8943-0028
Hairong YaoDepartment of Obstetrics & Gynecology, Cangzhou Central Hospital, Hebei 061001, China.
Liang ZhangDepartment of Obstetrics & Gynecology, Cangzhou Central Hospital, Hebei 061001, China.
Dongkui XuDepartment of Obstetrics & Gynecology, Cangzhou Central Hospital, Hebei 061001, China.
Qian LiDepartment of Obstetrics & Gynecology, Cangzhou Central Hospital, Hebei 061001, China.
Ying LiDepartment of Obstetrics & Gynecology, Cangzhou Central Hospital, Hebei 061001, China.
Cangzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we aimed to assess the independent prognostic value of miR-361-3p in terms of overall survival (OS) and recurrence-free survival (RFS) in cervical cancer, as well as its possible regulative network. A retrospective analysis was performed by using data from the Cancer Genome Atlas-Cervical Cancer (TCGA-CESC). Results showed that decreased miR-361-3p expression was associated with lymphovascular invasion and poor responses to primary therapy. The patients with recurrence and the deceased cases had substantially lower miR-361-3p expression compared to their respective controls. By generating Kaplan-Meier curves of OS and RFS, we found that high miR-361-3p expression was associated with better survival outcome. More importantly, univariate and multivariate analysis confirmed that high miR-361-3p expression was an independent indicator of favorable OS (HR: 0.377, 95% CI: 0.233-0.608,

Indexed as

Adaptor Proteins, Signal TransducingAdultAgedAntigens, CDBiomarkers, TumorBone Morphogenetic ProteinsDisease-Free SurvivalFemaleGenetic MarkersHistone DeacetylasesHumansMicroRNAsMiddle AgedPhosphoproteinsReceptors, TransferrinRepressor ProteinsAdaptor Proteins, Signal TransducingAntigens, CDBiomarkers, TumorBone Morphogenetic ProteinsCD71 antigenGenetic MarkersHistone DeacetylasesMicroRNAsMIRN361 microRNA, humanMTA1 protein, humanPhosphoproteinsReceptors, TransferrinRepressor ProteinsSOST protein, humanTrans-ActivatorsTranscription FactorsYAP1 protein, humanYAP-Signaling Proteins

Identifiers

PMID30344797
PMCPMC6174793
OpenAlexW2892412687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.