Evidence map›Paper›PMID 30344733›Full record

ArticleOncology letters2018

Intra-tumoral treatment with oxygen-ozone in glioblastoma: A systematic literature search and results of a case series.

Richard Megele, Markus J Riemenschneider, Frank Dodoo-Schittko, Matthias Feyrer, Andrea Kleindienst

Abstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Systemic Review: Ozone: A Potential New Chemotherapy.International journal of molecular sciences · 2021
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Medical ozone induces proliferation and migration inhibition through ROS accumulation and PI3K/AKT/NF-κB suppression in human liver cancer cells in vitro.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Richard MegeleDepartment of Neurosurgery, Klinikum St. Marien, D-92224 Amberg, Germany.
Markus J RiemenschneiderDepartment of Neuropathology, Regensburg University Hospital, D-93053 Regensburg, Germany.
Frank Dodoo-SchittkoMedical Sociology, Institute of Epidemiology and Preventative Medicine, University of Regensburg, D-93053 Regensburg, Germany.
Matthias FeyrerDepartment of Radiology, Klinikum St. Marien, D-92224 Amberg, Germany.
Andrea KleindienstDepartment of Neurosurgery, Klinikum St. Marien, D-92224 Amberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite progress in surgery and radiochemotherapy, the prognosis of glioblastoma (GB) remains poor. GB cells exhibit a preference for hypoxia to maintain their tumor-forming capacity. Treatment strategies utilizing oxygen (O

Indexed as

glioblastomaintra-tumoral treatmentoxygenozone

Identifiers

PMID30344733
PMCPMC6176341

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.