ArticlePakistan journal of medical sciences
Post hysteroscopic progesterone hormone therapy in the treatment of endometrial polyps.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Endometrial polyps recurrence: risk factors, prevention, and management.Open medicine (Warsaw, Poland) · 2026Review
- The regulation of intestinal flora on host's genes may play an essential role in the development of endometrial hyperplastic processes in yang deficiency individuals.International journal of clinical and experimental pathology · 2024Article
- Chronic endometritis increases the recurrence of endometrial polyps in premenopausal women after hysteroscopic polypectomy.BMC women's health · 2023Article
- Additional dydrogesterone for the treatment of chronic endometritis treated with antibiotic in premenopausal women with endometrial polyps: a retrospective cohort study.BMC women's health · 2022Observational
- Advanced uterine adenosarcoma with sarcomatous overgrowth in a young woman: A case report.Medicine · 2019Article
- Endometrial polyps: Pathogenesis, sequelae and treatment.SAGE open medicine · 2019Review
- Impact of Progesterone Therapy on Treatment Outcomes and Recurrence After Hysteroscopic Polypectomy.Nigerian medical journal : journal of the Nigeria Medical AssociationReview
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Authors and funding
5 authors.
Funding
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Abstract
objectiveTo find out the clinical effects of post hysteroscopic progesterone hormone therapy in the treatment of endometrial polyps in terms of clinical outcome and the expression of endometrial Vascular Endothelial Growth Factor (VEGF).
methodsNinety-eight patients who were confirmed as endometrial polyp in the hospital from April 2014 and December 2016 were selected and divided into treatment group and a control group using random number table, 49 in each group. Patients in both groups were given hysteroscopic operation. Patients in the treatment group were treated by progesterone hormone drugs after hysteroscopic operation, while patients in the control group were not given progesterone hormone. The changes of menstrual blood volume, menstrual cycle and expression of VEGF were compared between the two groups after treatment, and the recurrence condition, thickness of endometrium and hemoglobin were followed up one year after treatment.
resultsThe pictorial blood loss assessment chart (PBAC) scores of patients in the two groups had no significant difference before treatment (P>0.05); but the score of the treatment group was much lower than that of the control group. The improvement rate of menstrual cycle of the treatment group was much higher than that of the control group, and the difference had statistical significance (P<0.05). Compared to before treatment, the serum VEGF level of the patients in both groups had a remarkable decline in the 1
conclusionPost hysteroscopic progesterone hormone therapy has favorable clinical effect in treating endometrial polyps as it can effectively prevent the recurrence of endometrial polyps, relieve the level of hemoglobin and reduce endometrial thickness.
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