ArticleFrontiers in aging neuroscience2018
Involvement of the Precuneus/Posterior Cingulate Cortex Is Significant for the Development of Alzheimer's Disease: A PET (THK5351, PiB) and Resting fMRI Study.
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In one paragraph
Article in Frontiers in aging neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 4 pooled it
4.6field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 4 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- Neurobiological correlates of Mild Behavioral Impairment: a systematic review and meta-analysis.Alzheimer's research & therapy · 2025Pooled it
- Convergent functional changes of the episodic memory impairment in mild cognitive impairment: An ALE meta-analysis.Frontiers in aging neuroscience · 2022Pooled it
- Diagnostic power of resting-state fMRI for detection of network connectivity in Alzheimer's disease and mild cognitive impairment: A systematic review.Human brain mapping · 2021Pooled it
- A Systematic Review of the Association between Amyloid-β and τ Pathology with Functional Connectivity Alterations in the Alzheimer Dementia Spectrum Utilizing PET Scan and rsfMRI.Dementia and geriatric cognitive disorders extraPooled it
- Effects of 52 weeks of precuneus rTMS in Alzheimer's disease patients: a randomized trial.Alzheimer's research & therapy · 2025Trial
- Precuneus magnetic stimulation for Alzheimer's disease: a randomized, sham-controlled trial.Brain : a journal of neurology · 2022Trial
- Neuroimaging analyses from a randomized, controlled study to evaluate plasma exchange with albumin replacement in mild-to-moderate Alzheimer's disease: additional results from the AMBAR study.European journal of nuclear medicine and molecular imaging · 2022Trial
- Non-invasive Neuromodulation Targeting Approach by Mapping Stimulations and Lesions That Modify Visual Memory.bioRxiv : the preprint server for biology · 2026Article
- Normal cerebral oxygen consumption and lactate levels in patients with Alzheimer's disease and Lewy body dementia.GeroScience · 2026Article
- Imaging markers of neuroinflammation in aging and Alzheimer's disease and related dementia: A comprehensive review.Neuroscience and biobehavioral reviews · 2025Review
- Neurophysiological Progression in Alzheimer's Disease: Insights From Dynamic Causal Modelling of Longitudinal Magnetoencephalography.Human brain mapping · 2025Article
- Age-related loss of large dendritic spines in the precuneus is statistically mediated by proteins which are predicted targets of existing drugs.Molecular psychiatry · 2025Article
- Reduced Functional Connectivity in Nucleus Accumbens Subregions Associates With Cognitive Changes in Alzheimer's Disease.Brain and behavior · 2025Article
- Structural covariance network patterns linked to neuropsychiatric symptoms in biologically defined Alzheimer's disease: Insights from the mild behavioral impairment checklist.Journal of Alzheimer's disease : JAD · 2025Article
- Revealing excitation-inhibition imbalance in Alzheimer's disease using multiscale neural model inversion of resting-state functional MRI.Communications medicine · 2025Article
- Multivariate Analyses with Two-Step Dimension Reduction for an Association Study BetweenBioengineering (Basel, Switzerland) · 2025Article
- Cognitive impact and brain structural changes in long COVID patients: a cross-sectional MRI study two years post infection in a cohort from Argentina.BMC neurology · 2024Article
- Detection of Alzheimer's Disease Using Hybrid Meta-ROI of MRI Structural Images.Diagnostics (Basel, Switzerland) · 2024Article
- Iron accumulation/overload and Alzheimer's disease risk factors in the precuneus region: A comprehensive narrative review.Aging medicine (Milton (N.S.W)) · 2024Review
- Neuroimaging correlates of Alzheimer's disease biomarker concentrations in a racially diverse high-risk cohort of middle-aged adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 5 institutions in 1 country.
Takamasa YokoiDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hirohisa WatanabeDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hiroshi YamaguchiBrain and Mind Research Center, Nagoya University, Nagoya, Japan.
Epifanio BagarinaoBrain and Mind Research Center, Nagoya University, Nagoya, Japan.
Michihito MasudaDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kazunori ImaiDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Aya OguraDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Reiko OhdakeBrain and Mind Research Center, Nagoya University, Nagoya, Japan.
Kazuya KawabataDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kazuhiro HaraDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yuichi RikuDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shinsuke IshigakiDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masahisa KatsunoDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shinichi MiyaoDepartment of Neurology, Meitetsu Hospital, Nagoya, Japan.
Katsuhiko KatoDepartment of Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shinji NaganawaDepartment of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ryuichi HaradaDepartment of Pharmacology, Tohoku University School of Medicine, Sendai, Japan.
Nobuyuki OkamuraDivision of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Kazuhiko YanaiDepartment of Pharmacology, Tohoku University School of Medicine, Sendai, Japan.
Mari YoshidaDepartment of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Nagakute, Japan.
Gen SobueDepartment of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya University · JPTohoku University · JPAichi Medical University · JPMeitetsu Hospital · JPTohoku Medical and Pharmaceutical University · JP
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
11C-PiB18F-THK5351astrocyteMAO-BMRIpositron emission tomography (PET)resting state network
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.