Observational studyWorld journal of gastroenterology2018
Practical fecal calprotectin cut-off value for Japanese patients with ulcerative colitis.
Observational study in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Surrogate markers of mucosal healing in inflammatory bowel disease: A systematic review.World journal of gastroenterology · 2021Pooled it
- Extracellular miRNAs in the serum and feces of mice exposed to high‑dose radiation.Biomedical reports · 2024Article
- Deep mucosal healing in ulcerative colitis: how deep is better?Frontiers in medicine · 2024Review
- Comparison of fecal calprotectin levels and endoscopic scores for predicting relapse in patients with ulcerative colitis in remission.World journal of gastroenterology · 2023Article
- Serum Leucine-Rich α2 Glycoprotein: A Biomarker for Predicting the Presence of Ulcerative Colitis but Not Ulcerative Proctitis.Journal of clinical medicine · 2022Article
- Predicting Ulcerative Colitis Relapse in Clinical Remission With Fecal Immunochemical Occult Blood Test or Prostaglandin E-Major Urinary Metabolite.Clinical and translational gastroenterology · 2022Article
- Endoscopy for assessment of mucosal healing in ulcerative colitis: time bound or response guided?Intestinal research · 2022Article
- Lymphocyte-to-monocyte ratio is a short-term predictive marker of ulcerative colitis after induction of advanced therapy.Gastroenterology report · 2022Article
- Further research on the clinical relevance of the ulcerative colitis colonoscopic index of severity for predicting 5-year relapse.International journal of colorectal disease · 2021Article
- Treatment Targets in Ulcerative Colitis: Is It Time for All In, including Histology?Journal of clinical medicine · 2021Review
- Fecal calprotectin is a useful biomarker for predicting the clinical outcome of granulocyte and monocyte adsorptive apheresis in ulcerative colitis patients: a prospective observation study.BMC gastroenterology · 2021Observational
- Early serum albumin changes in patients with ulcerative colitis treated with tacrolimus will predict clinical outcome.World journal of gastroenterology · 2021Article
- Fecal calprotectin as a noninvasive test to predict deep remission in patients with ulcerative colitis.Medicine · 2021Observational
- Can fecal calprotectin accurately identify histological activity of ulcerative colitis? A meta-analysis.Therapeutic advances in gastroenterology · 2021Article
- Prostaglandin E-Major Urinary Metabolite Predicts Relapse in Patients With Ulcerative Colitis in Clinical Remission.Clinical and translational gastroenterology · 2020Observational
- Baseline levels of dynamic CD4BMC gastroenterology · 2020Article
- Patient knowledge of fecal calprotectin in inflammatory bowel disease (IBD): An observational study in Mexico.F1000Research · 2020Article
- Clinical Performance of Fecal Calprotectin Reagents Based on the Colloidal Gold Agglutination Method for Evaluating the Differential Diagnosis between Inflammatory Bowel Disease and Irritable Bowel Syndrome in Adults and Children with Gastrointestinal Symptoms (SCALE 1).Inflammatory intestinal diseasesArticle
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine appropriate fecal calprotectin cut-off values for the prediction of endoscopic and histologic remission in Japanese patients with ulcerative colitis (UC).
methodsWe performed a cross-sectional observational study of 131 Japanese patients with UC and measured fecal calprotectin levels by fluorescence enzyme immunoassay. The clinical activity of UC was assessed with the partial Mayo score (PMS). Relapse was defined as increase of PMS by 2 points or more in stool frequency or rectal bleeding subscore. The endoscopic and histologic activities of UC were evaluated in 50 patients within a 2-mo period from fecal sampling. Endoscopic activity was determined by Mayo endoscopic subscore, Rachmilewitz endoscopic index, and ulcerative colitis endoscopic index of severity. The histologic grade of inflammation was evaluated with biopsy specimens obtained from the endoscopically most severely inflamed site, according to the scheme by Matts grade and Riley's score.
resultsFecal calprotectin levels varied from 1-20783 μg/g. There was a significant correlation between the partial Mayo score and fecal calprotectin levels (
conclusionFecal calprotectin is a predictive biomarker for endoscopic and histologic remission in Japanese patients with UC.
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