Evidence map›Paper›PMID 30344418›Full record

ReviewWorld journal of gastroenterology2018

Towards hepatitis C virus elimination: Egyptian experience, achievements and limitations.

Dalia Omran, Mohamed Alboraie, Rania A Zayed, Mohamed-Naguib Wifi, Mervat Naguib, Mohamed Eltabbakh, Mohamed Abdellah, Ahmed Fouad Sherief, Sahar Maklad, Heba Hamdy Eldemellawy and 3 more

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04757272 (Does Hepatitis C Management Protect Egyptian Population Against Severe Corona Virus Disease-2019), which is not on this map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04757272 completednot on this mapstarted 2020, after this paper: background citation

Does Hepatitis C Management Protect Egyptian Population Against Severe Corona Virus Disease-2019 (COVID-19)?

TypeobservationalSponsorZagazig UniversityRan2020 to 2022Enrolled2,106ConditionsCorona Virus Infection, Hepatitis
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 151 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Therapeutic, preventive, and pathogenetic advances in viral hepatitis.Frontiers in cellular and infection microbiology · 2026
    Review
  8. Article
  9. A systematic PCR record-based re-call of HCV-RNA-positive people enables re-linkage to care and HCV elimination in Austria - The ELIMINATE project.Liver international : official journal of the International Association for the Study of the Liver · 2024
    Article
  10. Article
  11. Review
  12. FAIR reporting of clinical trials for public health practice.Proceedings of the European Academy of Sciences & Arts · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Editorial: Effective Direct-Acting Antiviral Treatments Support Global and National Programs to Eliminate Hepatitis C.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Dalia OmranDepartment of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo 11651, Egypt. daliaomran@kasralainy.edu.eg.
Mohamed AlboraieDepartment of Internal Medicine, Al-Azhar University, Cairo 11651, Egypt.
Rania A ZayedDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, Cairo 11651, Egypt.
Mohamed-Naguib WifiDepartment of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11599, Egypt.
Mervat NaguibDepartment of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11599, Egypt.
Mohamed EltabbakhDepartment of Tropical Medicine, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.
Mohamed AbdellahDepartment of Internal Medicine, Al-Azhar University, Cairo 11651, Egypt.
Ahmed Fouad SheriefDepartment of Tropical Medicine, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.
Sahar MakladNational Hepatology and Tropical Medicine Research Institute, Cairo 11599, Egypt.
Heba Hamdy EldemellawyDepartment of Internal Medicine, Faculty of Medicine, Beni-Suef University, Beni-Suef 62511, Egypt.
Omar Khalid SaadFaculty of Medicine, Ain Shams University, Cairo 11566, Egypt.
Doaa Mohamed KhamissDepartment of Clinical and Chemical Pathology, El-monera hospital, Ministry of Health, Cairo 11562, Egypt.
Mohamed El KassasDepartment of Endemic Medicine, Faculty of Medicine, Helwan University, Cairo 11599, Egypt.
Ain Shams University · EGAl-Azhar University · EGCairo University · EGBeni-Suef University · EGHelwan University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, more than one million people die each year from hepatitis C virus (HCV) related diseases, and over 300 million people are chronically infected with hepatitis B or C. Egypt used to be on the top of the countries with heavy HCV burden. Some countries are making advances in elimination of HCV, yet multiple factors preventing progress; remain for the majority. These factors include lack of global funding sources for treatment, late diagnosis, poor data, and inadequate screening. Treatment of HCV in Egypt has become one of the top national priorities since 2007. Egypt started a national treatment program intending to provide cure for Egyptian HCV-infected patients. Mass HCV treatment program had started using Pegylated interferon and ribavirin between 2007 and 2014. Yet, with the development of highly-effective direct acting antivirals (DAAs) for HCV, elimination of viral hepatitis has become a real possibility. The Egyptian National Committee for the Control of Viral Hepatitis did its best to provide Egyptian HCV patients with DAAs. Egypt adopted a strategy that represents a model of care that could help other countries with high HCV prevalence rate in their battle against HCV. This review covers the effects of HCV management in Egyptian real life settings and the outcome of different treatment protocols. Also, it deals with the current and future strategies for HCV prevention and screening as well as the challenges facing HCV elimination and the prospect of future eradication of HCV.

Indexed as

Antiviral AgentsDisease EradicationDrug Therapy, CombinationEgyptHepacivirusHepatitis C, ChronicHumansMass ScreeningNational Health ProgramsPrevalenceAntiviral AgentsDirect acting antiviralsEgyptEliminationHepatitis C virusLimitationsScreening

Identifiers

PMID30344418
PMCPMC6189850
OpenAlexW2898026627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.