ArticleCurrent biology : CB2018
Correlated Evolution of Two Copulatory Organs via a Single cis-Regulatory Nucleotide Change.
Article in Current biology : CB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 110 citations in OpenAlex.
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- The role of the epidermis enhancer element in positive and negative transcriptional regulation of ebony in Drosophila melanogaster.G3 (Bethesda, Md.) · 2022Article
- Sex-specific evolution of a Drosophila sensory system via interacting cis- and trans-regulatory changes.Evolution & development · 2022Article
- Pleiotropy facilitates parallel adaptation in sticklebacks.Molecular ecology · 2022Article
- Leg length and bristle density, both necessary for water surface locomotion, are genetically correlated in water striders.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- A morphological trait involved in reproductive isolation between Drosophila sister species is sensitive to temperature.Ecology and evolution · 2021Article
- Enhancer evolutionary co-option through shared chromatin accessibility input.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Adaptation via pleiotropy and linkage: Association mapping reveals a complex genetic architecture within the sticklebackEvolution letters · 2020Article
- Co-evolving wing spots and mating displays are genetically separable traits in Drosophila.Evolution; international journal of organic evolution · 2020Article
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10 authors at 6 institutions in 2 countries.
Funding
Abstract
Diverse traits often covary between species [1-3]. The possibility that a single mutation could contribute to the evolution of several characters between species [3] is rarely investigated as relatively few cases are dissected at the nucleotide level. Drosophila santomea has evolved additional sex comb sensory teeth on its legs and has lost two sensory bristles on its genitalia. We present evidence that a single nucleotide substitution in an enhancer of the scute gene contributes to both changes. The mutation alters a binding site for the Hox protein Abdominal-B in the developing genitalia, leading to bristle loss, and for another factor in the developing leg, leading to bristle gain. Our study suggests that morphological evolution between species can occur through a single nucleotide change affecting several sexually dimorphic traits. VIDEO ABSTRACT.
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