Evidence map›Paper›PMID 30344005›Full record

ArticleThe International journal on drug policy2018

Use of rapid fentanyl test strips among young adults who use drugs.

Maxwell S Krieger, William C Goedel, Jane A Buxton, Mark Lysyshyn, Edward Bernstein, Susan G Sherman, Josiah D Rich, Scott E Hadland, Traci C Green, Brandon D L Marshall

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in The International journal on drug policy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04372238 (The Rhode Island Prescription and Illicit Drug Study Responding to Fentanyl and Associated Harms), which is not on this map. Cited by 113 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 2 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04372238 nacompletednot on this mapstarted 2020, after this paper: background citation

The Rhode Island Prescription and Illicit Drug Study Responding to Fentanyl and Associated Harms

TypeinterventionalSponsorBrown UniversityRan2020 to 2024Enrolled509ConditionsOpioid Overdose, Drug OverdoseArmsRAPIDS Intervention, Standard OEND
3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 2 syntheses or guidelines pooled it, 185 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Assessment of Test Strips for Detection of Fentanyl in Powders.Prevention science : the official journal of the Society for Prevention Research · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Observational
  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Maxwell S KriegerDepartment of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.
William C GoedelDepartment of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.
Jane A BuxtonSchool of Population and Public Health, University of British Columbia, Vancouver, Canada; British Columbia Centre for Disease Control, Vancouver, Canada.
Mark LysyshynSchool of Population and Public Health, University of British Columbia, Vancouver, Canada; Vancouver Coastal Health, Vancouver, Canada.
Edward BernsteinDepartment of Emergency Medicine, Grayken Center for Addiction, Boston University School of Medicine, Boston, USA; Department of Pediatrics, Grayken Center for Addiction, Boston Medical Center, Boston, USA.
Susan G ShermanDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Josiah D RichDepartment of Epidemiology, School of Public Health, Brown University, Providence, RI, USA; Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, USA.
Scott E HadlandDepartment of Emergency Medicine, Grayken Center for Addiction, Boston University School of Medicine, Boston, USA; Department of Pediatrics, Grayken Center for Addiction, Boston Medical Center, Boston, USA.
Traci C GreenDepartment of Epidemiology, School of Public Health, Brown University, Providence, RI, USA; Department of Emergency Medicine, Grayken Center for Addiction, Boston University School of Medicine, Boston, USA; Department of Pediatrics, Grayken Center for Addiction, Boston Medical Center, Boston, USA; Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, USA.
Brandon D L MarshallDepartment of Epidemiology, School of Public Health, Brown University, Providence, RI, USA. Electronic address: brandon_marshall@brown.edu.
Brown University · USBoston University · USUniversity of British Columbia · CAJohns Hopkins University · US

Funding

Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI JOSIAH D RICH · 2018 to 2026
$23.4M
Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI ZACHARY Franklin MEISEL · 2015 to 2026
$20.7M
Midcareer Investigator Award in Patient Oriented ResearchK24DA022112 · NIDA · MIRIAM HOSPITAL · PI RICH, JOSIAH D · 2008 to 2017
$1.7M
Collaborative Care Office-Based Opioid Treatment for Adolescents and Young AdultsK23DA045085 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI HADLAND, SCOTT EVAN · 2018 to 2022
$1.1M
NIDA NIH HHS K23 DA045085NIDA NIH HHS K24 DA022112NIDA NIH HHS L40 DA042434NIDA NIH HHS P30 DA040500NIGMS NIH HHS P20 GM125507
6 · The paper itself

Abstract

backgroundThe overdose epidemic has been exacerbated by a dramatic increase in deaths involving illicitly manufactured fentanyl (IMF). Drug checking is a novel strategy to identify IMF in illicit drugs. We examined the uptake and acceptability of rapid fentanyl test strips among young adults.

methodsFrom May to September 2017, we recruited 93 young adults in Rhode Island who reported injecting drugs or using heroin, cocaine, or illicitly obtained prescription pills in the past 30 days. Participants were asked to test either their urine after drug use (post-consumption) or a drug sample prior to use (pre-consumption) using rapid fentanyl test strips. After a questionnaire and a brief training, participants received ten strips for their personal use and were asked to return for a one-month follow-up visit, which assessed the uptake and acceptability of the rapid strips tests and the behavioral outcomes associated with receipt of a positive test.

resultsOf the 81 (87%) participants who returned for follow-up and who had complete data, the mean age was 27, 45 (56%) were male, and 37 (46%) were non-white. A total of 62 participants (77%) reported using at least one test strip. Of these, 31 (50%) received at least one positive result. A positive result was associated with older age, homelessness, heroin use, injection drug use, ever witnessing an overdose, and concern about overdose or drugs being laced with fentanyl (all p < 0.05). Receiving a positive result was significantly associated with reporting a positive change in overdose risk behavior between baseline and follow-up (p ≤  0.01). Among all participants, 79 (98%) reported confidence in their ability to use the test strips and 77 (95%) wanted to use them in the future.

conclusionsYoung adults reported high uptake and acceptability of fentanyl test strips to detect IMF in illicit drugs.

Indexed as

Reagent StripsAdultAnalgesics, OpioidDrug OverdoseFemaleFentanylHeroinHumansIllicit DrugsMaleOpioid-Related DisordersRhode IslandRisk-TakingSubstance Abuse, IntravenousSurveys and QuestionnairesYoung AdultAnalgesics, OpioidFentanylHeroinIllicit DrugsReagent StripsAcceptabilityFentanylHarm reductionOpioidsOverdoseUptake

Identifiers

PMID30344005
PMCPMC6701177
OpenAlexW2897909773

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.