ReviewCurrent reviews in musculoskeletal medicine2018
Treatment of Muscle Injuries with Platelet-Rich Plasma: a Review of the Literature.
Review in Current reviews in musculoskeletal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07566039 (Prospective Cohort Study of Athletes Following an Injection of Platelet-Poor Plasma Into an Acute Muscle Injury), which is not on this map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Cohort Study of Athletes Following an Injection of Platelet-Poor Plasma Into an Acute Muscle Injury
Who cites it
24 citing papers in PubMed.
- Efficacy of platelet-rich plasma in grade 2 hamstring muscle injuries: results from a randomized controlled trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Trial
- Comparative Efficacy of Platelet-Rich Plasma and Dry Needling for Management of Trigger Points in Masseter Muscle in Myofascial Pain Syndrome Patients: A Randomized Controlled Trial.Journal of oral & facial pain and headache · 2022Trial
- Mouse Models of Muscle Fibrosis: Mechanisms, Methods, and Applications.Biomedicines · 2026Review
- Controlled delivery of PRP from decellularized extracellular matrix enhances skeletal muscle regeneration.Scientific reports · 2025Article
- Case series: effects of platelet-rich plasma (PRP) on the recovery of bilateral muscle injuries after removal of semitendinosus and gracilis grafts in bilateral anterior cruciate ligament (ACL) reconstruction.Journal of surgical case reports · 2025Article
- Does Changes in the Muscles Beneath the Submucosal Tissues Necessitate a Novel Strategy in the Medical Management of OSMF: A Systematic Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Review
- [Muscle injuries: the importance of high-resolution dynamic sonography in diagnostics, treatment and monitoring].Orthopadie (Heidelberg, Germany) · 2024Article
- Medial Gastrocnemius Strain: Clinical Aspects and Algorithmic Approach.Medical journal of the Islamic Republic of Iran · 2024Article
- Accessory Tibionavicular Muscle: An Unusual Cause of Medial Ankle Pain.The Indian journal of radiology & imaging · 2023Article
- Effect of platelet indices on postoperative pain and edema in bimaxillary surgery.Saudi medical journal · 2023Article
- Lower Extremity Muscle Injuries in the Overhead Athlete.Current reviews in musculoskeletal medicine · 2022Review
- Sport-Specific Rehabilitation, but Not PRP Injections, Might Reduce the Re-Injury Rate of Muscle Injuries in Professional Soccer Players: A Retrospective Cohort Study.Journal of functional morphology and kinesiology · 2022Article
- VEGF-attenuated platelet-rich plasma improves therapeutic effect on cartilage repair.Biomaterials science · 2022Article
- Current updates in image-guided musculoskeletal interventions.Journal of clinical orthopaedics and trauma · 2021Article
- Ultrasound Imaging in Sport-Related Muscle Injuries: Pitfalls and Opportunities.Medicina (Kaunas, Lithuania) · 2021Review
- Next Stage Approach to Tissue Engineering Skeletal Muscle.Bioengineering (Basel, Switzerland) · 2020Review
- Novel Insights into the Pathogenesis of Spinal Sarcopenia and Related Therapeutic Approaches: A Narrative Review.International journal of molecular sciences · 2020Review
- Platelet-Rich Plasma Shortens Return to Play in National Football League Players With Acute Hamstring Injuries.Orthopaedic journal of sports medicine · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThis review discusses the current literature regarding the use of platelet-rich plasma (PRP) in the treatment of muscle strain injuries. Case series as well as experimental trials for both human and animal models are covered. RECENT
findingsMultiple studies have examined outcomes for the use of PRP in the treatment of muscle strain injuries. PRP has been shown to promote muscle recovery via anabolic growth factors released from activated platelets, and in doing so, potentially reduces pain, swelling, and time for return to play. In vitro studies support the regenerative potential of PRP for acute soft tissue injuries. Multiple clinical case series for PRP injections in the setting of muscle strains demonstrate imaging evidence for faster healing, less swelling, which can decrease time for return to play. These studies, however, are retrospective in nature, and few randomized controlled studies exist to demonstrate a clear clinical benefit. Additionally, there is tremendous heterogeneity regarding the injectant preparation, optimum platelet concentration, presence of leukocytes, and volume of PRP which should be administered as well as number of and timing of treatments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.