Evidence map›Paper›PMID 30343377›Full record

ArticleInternational urogynecology journal2019

Defecatory dysfunction and other clinical variables are predictors of pessary discontinuation.

Erin G Dengler, Louisa A Mounsey, Francesca Gines, Manahil Agha, Terri Long, Elizabeth J Geller

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Article in International urogynecology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  5. Observational
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Erin G DenglerSchool of Medicine, University of North Carolina at Chapel Hill, 321 S Columbia St., Chapel Hill, NC, 27516, USA.
Louisa A MounseySchool of Medicine, University of North Carolina at Chapel Hill, 321 S Columbia St., Chapel Hill, NC, 27516, USA.
Francesca GinesUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Manahil AghaUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Terri LongUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Elizabeth J GellerDivision of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina at Chapel Hill, CB 7570 Old Clinic, Chapel Hill, NC, 27599-7570, USA. egeller@med.unc.edu.ORCID 0000-0002-2376-2249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisPessaries provide first-line therapy for women with pelvic organ prolapse (POP) and stress urinary incontinence (SUI). The primary hypothesis was that defecatory dysfunction was associated with pessary discontinuation.

methodsThis was a retrospective cohort study of all women undergoing first pessary placement at one academic center from April 2014 to January 2017. Defecatory dysfunction was defined as the presence of constipation, rectal straining, rectal splinting, and/or incomplete defecation. Pessary discontinuation was defined as <1 year of pessary use and not using one at the most recent visit. Descriptive statistics; Person's chi-square, Fisher's exact, and Student's t test, and multivariate logistic regression analysis were used where appropriate.

resultsCharts of 1092 women were reviewed and 1071 were included. Mean age was 62 ± 15 years, mean body mass index (BMI) 28 ± 6 kg/m

conclusionsPessary discontinuation was common, and defecatory dysfunction in the form of incomplete defecation had the strongest association with discontinuation. Understanding predictive factors of pessary discontinuation may help guide clinicians and patients when choosing treatment options for pelvic floor dysfunction.

Indexed as

DefecationAgedAged, 80 and overCase-Control StudiesConstipationFemaleHumansMiddle AgedPatient CompliancePelvic Organ ProlapsePessariesRectal DiseasesRetrospective StudiesUrinary Incontinence, StressDefecatory dysfunctionPessaryPessary discontinuationPredictors

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.