Evidence map›Paper›PMID 30343121›Full record

ArticleJournal of affective disorders2019

Effects of childhood trauma on adult moral decision-making: Clinical correlates and insights from bipolar disorder.

Emmett M Larsen, Luz H Ospina, Armando Cuesta-Diaz, Antonio Vian-Lains, George C Nitzburg, Sandra Mulaimovic, Asya Latifoglu, Rosarito Clari, Katherine E Burdick

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Do Adverse Childhood Experiences Make Us More Utilitarian in Moral Dilemmas?Psychology research and behavior management · 2024
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Emmett M LarsenDepartments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: emtlarsen@gmail.com.
Luz H OspinaDepartments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Armando Cuesta-DiazDepartments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Antonio Vian-LainsDepartments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
George C NitzburgDivision of Psychiatry Research, The Zucker Hillside Hospital, Northwell Health System, Glen Oaks, NY, USA; Teachers College, Columbia University, New York, NY, USA.
Sandra MulaimovicDepartments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Asya LatifogluDepartments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Teachers College, Columbia University, New York, NY, USA.
Rosarito ClariDepartments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Katherine E BurdickDepartments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Psychiatry, James J. Peters Veterans Affairs Hospital, Bronx, NY, USA; Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Icahn School of Medicine at Mount Sinai · USBrigham and Women's Hospital · USColumbia University · USNorthwell Health · US

Funding

Understanding the Neurocognitive Heterogeneity in Bipolar DisorderR01MH100125 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BURDICK, KATHERINE ELIZABETH · 2013 to 2017
$2.1M
Neurocognitive Heterogeneity in Patients with Psychosis _ A Dimensional ApproachI01CX000995 · VA · JAMES J PETERS VA MEDICAL CENTER · PI BURDICK, KATHERINE ELIZABETH · 2014 to 2019
–
CSRD VA I01 CX000995NIMH NIH HHS R01 MH100125
6 · The paper itself

Abstract

backgroundChildhood adversity has been shown to exert profound effects on basic psychological processes well into adulthood. Some of these processes, such as those related to reward and emotion, play critical roles in moral decision-making. As a population with high rates of childhood trauma as well as heterogenous clinical presentation, individuals with bipolar disorder (BD) constitute an enriched group in which to examine the correlates of trauma and other clinical variables with moral cognition.

methods62 euthymic BD patients and 27 controls responded to moral dilemma scenarios and completed the Childhood Trauma Questionnaire.

resultsResults revealed a main effect of diagnosis on moral decision-making only when both personal force and an intention were required, indicating a more utilitarian style in BD patients relative to controls. Several interesting patterns also emerged regardless of diagnostic status. Higher ratings of physical neglect were significantly associated with higher ratings of acceptability (a utilitarian tendency) across dilemma types, and a similar pattern was observed at the trend level for experiences of emotional neglect. Significant main effects on moral decision-making were also observed for sex, illness duration, and history of psychotic features in the BD sample. LIMITATIONS: The present study is limited by the self-reported nature of the CTQ and by the small number of trials of moral dilemmas. In addition, practical and clinical implications of the moral dilemmas paradigm are limited due to its abstract nature.

conclusionsOur results indicate that certain clinical features as well as childhood maltreatment (in particular neglect) may significantly impact moral decision making in adult life. Surprisingly, childhood trauma was associated with a more utilitarian style, which is in the opposite direction from previous effects shown in PTSD. Although speculative, our results suggest that there may be a protective quality associated with utilitarian moral decision-making tendencies.

Indexed as

Decision MakingMoralsAdultAdult Survivors of Child AbuseBipolar DisorderEmotionsFemaleHumansMaleRetrospective StudiesSelf ReportSurveys and QuestionnairesBipolar disorderChildhood traumaMoral decision-makingMoral dilemmas

Identifiers

PMID30343121
PMCPMC6287939
OpenAlexW2894986506

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.