Trial reportBMC cancer2018
Fear of cancer recurrence trajectory during radiation treatment and follow-up into survivorship of patients with breast cancer.
Trial report in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02599506 (Fear of Cancer Recurrence), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Fear of Cancer Recurrence (FoR) Trajectory During Radiation Treatment and Follow-up Into Survivorship of 100 Breast Cancer patients-a Pilot Study
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Fear of disease progression among breast cancer patients in China: a meta-analysis of studies using the fear of progression questionnaire short form.Frontiers in psychology · 2023Pooled it
- CBT-based Online Self-help Training to Reduce Fear and Distress After Cancer (CAREST Randomized Trial): 24 Months Follow-up Using Latent Growth Models and Latent Class Analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Trial
- Fear of Progression in Pediatric Cancer Patients and Their Parents: Trajectories, Prevalence, and Correlates Across Acute Treatment and Follow-Up Care.Psycho-oncology · 2026Article
- Trajectories of dyadic fear of cancer recurrence in breast cancer couples: a prospective observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Trajectories of postoperative nutritional risk changes in patients with oesophageal cancer and their relationship with symptom recovery-a multicentre longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Exploring determinants of fear of cancer recurrence in postoperative colorectal cancer patients: a random forest model approach.Journal of cancer research and clinical oncology · 2025Article
- The influence of cancer treatments on long-term psychological outcomes and quality of life in breast cancer patients.BMC cancer · 2025Article
- Association between fear of cancer recurrence and emotional distress in breast cancer: a latent profile and moderation analysis.Frontiers in psychiatry · 2025Article
- Effects of repetitive transcranial magnetic stimulation on fear of cancer recurrence and its underlying neuromechanism.Contemporary clinical trials communications · 2024Article
- Protective Factors against Fear of Cancer Recurrence in Breast Cancer Patients: A Latent Growth Model.Cancers · 2023Article
- Symptom trajectories in patients with breast cancer: An integrative review.International journal of nursing sciences · 2022Review
- Not as Stable as We Think: A Descriptive Study of 12 Monthly Assessments of Fear of Cancer Recurrence Among Curatively-Treated Breast Cancer Survivors 0-5 Years After Surgery.Frontiers in psychology · 2020Article
- An observational mixed-methods approach to investigate the fear of cancer recurrence cognitive and emotional model by Lee-JonesEcancermedicalscience · 2019Article
- Development, acceptability and feasibility of a communication skills training package for therapeutic radiographers to reduce fear of recurrence development in breast cancer patients (FORECAST2).Pilot and feasibility studies · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundFear of cancer recurrence (FCR) has been shown to be higher in patients treated with external beam radiotherapy (RT) compared to those untreated. However, little is known about the dynamics of patient's FCR during and after RT. The aim of this study was to examine FCR levels in a longitudinal panel design with breast cancer patients receiving RT.
methodsConsecutive newly-diagnosed breast cancer patients (n = 94) attending a single cancer centre were invited to complete a 7-item FCR scale (FCR7) that was collected weekly by paper instrument and at a follow-up phone call 6-8 weeks after completion of RT. Descriptive statistics, and Latent Growth Curve Modelling (LGCM) were utilised to analyse the data.
resultsWomen who were younger, single/separated, had chemotherapy, had extra boost radiation treatment, taking Herceptin and treated by 4-field technique reported higher recurrence fear at baseline. There was strong evidence of substantial variation in the trajectory of FCR (z = - 3.54, p < .0001). The average trajectory of FCR over RT was negative (unstandardized estimate = - 0.59) and associated with FCR follow-up level (standardised estimate = 0.36, z = 3.05, p < .002), independent of baseline recurrence fears.
conclusionPatients vary in their trajectory of recurrence fears over RT which predicts FCR approximately 2 months following treatment. Review appointments by therapy radiographers presents an opportunity to intervene in FCR trajectories.
trial registrationClinicalTrials.gov: NCT02599506 . Prospectively registered on 11th March 2015.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.