Evidence map›Paper›PMID 30342491›Full record

ArticleBMC cancer2018

Shear wave elastography in the evaluation of level VI lymph nodes in papillary thyroid carcinoma: combined with gray-scale ultrasound ex vivo.

Wanying Chang, Lei Tang, Caiwei Lu, Min Wu, Man Chen

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wanying ChangDepartment of Diagnostic Ultrasound, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xian Xia Road, Shanghai, 200336, China.
Lei TangDepartment of Diagnostic Ultrasound, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xian Xia Road, Shanghai, 200336, China.
Caiwei LuDepartment of Pathology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Rui Jin 2nd Road, Shanghai, 200025, China.
Min WuDepartment of Pathology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Rui Jin 2nd Road, Shanghai, 200025, China.
Man ChenDepartment of Diagnostic Ultrasound, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xian Xia Road, Shanghai, 200336, China. maggiech3138@126.com.ORCID http://orcid.org/0000-0002-7500-0369
Shanghai Jiao Tong University · CN

Funding

Natural Science Foundation of Shanghai 18ZR1434800
6 · The paper itself

Abstract

backgroundThe evaluation of cervical lymph nodes is very important for patients with papillary thyroid carcinoma (PTC). Conventional ultrasound is recommended to assess the status of cervical lymph nodes but the diagnostic performance is not satisfying especially in level VI lymph nodes. Recently, shear wave elastography has shown great potential in diagnosis. Therefore, this study aimed at exploring the value of shear wave elastography in ultrasound evaluation for level VI lymph nodes in papillary thyroid carcinoma. Because Hashimoto's thyroiditis may influence the diagnostic performance, a subgroup was also analysed that included only lymph nodes from PTC without Hashimoto's thyroiditis.

methodsEighty-Seven level VI lymph nodes from 22 consecutive patients with papillary thyroid carcinoma were evaluated by gray-scale ultrasound and SWE in condition of ex vivo before rapid frozen section. Gray-scale ultrasound and shear wave elastography indexes of metastatic and non-metastatic lymph nodes were evaluated by statistical analysis separately in all patients and in patients without Hashimoto's thyroiditis. Indexes included long diameter, short diameter, short-to-long diameter ratio (S/L ratio), E

resultsIn all patients, significant indexes included short diameter (p = 0.009), S/L ratio (p = 0.003), E

conclusionShear wave elastography can provide additional information for ultrasound evaluation of level VI lymph nodes in papillary thyroid carcinoma, especially in papillary thyroid carcinoma without Hashimoto's thyroiditis.

Indexed as

AdultAgedCarcinoma, PapillaryElasticity Imaging TechniquesFemaleHumansLymphatic MetastasisMaleMiddle AgedThyroid Cancer, PapillaryThyroid NeoplasmsUltrasonographyGray-scale ultrasoundLevel VI lymph nodesPapillary thyroid carcinomaShear wave elastography

Identifiers

PMID30342491
PMCPMC6195959
OpenAlexW2897523403

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.