Evidence map›Paper›PMID 30342361›Full record

ArticleHearing research2018

Unusual mechanical processing of sounds at the apex of the Guinea pig cochlea.

Alberto Recio-Spinoso, John S Oghalai

Abstract read
In one paragraph

Article in Hearing research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Tuning and Timing of Organ of Corti Vibrations at the Apex of the Intact Chinchilla Cochlea.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Alberto Recio-SpinosoInstituto de Investigación en Discapacidades Neurológicas, Universidad de Castilla-La Mancha, Albacete, Spain. Electronic address: reci0001@umn.edu.
John S OghalaiCaruso Department of Otolaryngology, University of Southern California, Los Angeles, CA, USA.
University of Castilla-La Mancha · ESUniversity of Southern California · US

Funding

Cochlear mechanics in the mouseR01DC014450 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI John S Oghalai · 2015 to 2026
$5.6M
PERIPHERAL MECHANISMS OF HEARINGR01DC000419 · NIDCD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI RUGGERO, MARIO A · 1989 to 2014
$5.3M
Mechanisms of cochlear synaptopathy after noise or blast traumaR01DC017741 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OGHALAI, JOHN S · 2020 to 2024
$3.1M
Stanford OHNS Core CenterP30DC010363 · NIDCD · STANFORD UNIVERSITY · PI RICCI, ANTHONY J · 2009 to 2016
$3.0M
Optical coherence tomography for 3D measures of cochlear mechanics in vivoR01DC013774 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OGHALAI, JOHN S · 2015 to 2019
$2.1M
NIDCD NIH HHS P30 DC010363NIDCD NIH HHS R01 DC000419NIDCD NIH HHS R01 DC013774NIDCD NIH HHS R01 DC014450NIDCD NIH HHS R01 DC017741
6 · The paper itself

Abstract

One of the tenets of mammalian auditory physiology is that the frequency selectivity at the cochlear base decreases as a function of stimulus level. Changes in frequency selectivity have been shown to be accompanied by changes in response phases as a function of stimulus level. The existence of such nonlinear properties has been revealed by the analysis of either direct or indirect recordings of mechanical vibrations of the cochlea. Direct measurements of cochlear mechanical vibrations, however, have been carried out with success primarily in cochlear regions that are tuned to frequencies >7 kHz, but not in regions sensitive to lower frequencies. In this paper we continue to analyze recently published data from measurements of sound-induced vibrations at four locations near the apex of the intact guinea pig cochlea, in a region encompassing approximately 25% of its total length. Analysis of the responses at all locations reveal level-dependent phase properties that are rather different from those usually reported at the base of the cochlea of laboratory animals such as the chinchilla. Cochlear group delays, for example, increase or remain constant with increasing stimulus. Similarly, frequency selectivity at all the regions increases as a function of stimulus level.

Indexed as

HearingMechanotransduction, CellularSoundAnimalsAuditory PathwaysCochleaFemaleGuinea PigsMaleMotionPressureVibrationApexCochleaGuinea pigNonlinearityOrgan of cortiVOCT

Identifiers

PMID30342361
PMCPMC13195637
OpenAlexW2894681587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.