Evidence map›Paper›PMID 30342360›Full record

ArticleEcotoxicology and environmental safety2019

Airway microbiome is associated with respiratory functions and responses to ambient particulate matter exposure.

Liping Wang, Haoxiang Cheng, Dongbin Wang, Bo Zhao, Jushan Zhang, Long Cheng, Pengfei Yao, Antonio Di Narzo, Yuan Shen, Jing Yu and 10 more

Abstract read
In one paragraph

Article in Ecotoxicology and environmental safety, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Review
  7. Article
  8. Review
  9. Air pollution-induced airway epithelial barrier dysfunction in COPD: a narrative review of mechanisms and therapeutic implications.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Gan-du-qing attenuates PMFrontiers in medicine · 2025
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Liping WangDepartment of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China; College of Environmental Science and Engineering, Tongji University, Shanghai, China.
Haoxiang ChengDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Dongbin WangSchool of Environment, Tsinghua University, Beijing, China.
Bo ZhaoSchool of Life Sciences, Tongji University, Shanghai, China.
Jushan ZhangDepartment of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China; College of Environmental Science and Engineering, Tongji University, Shanghai, China.
Long ChengSchool of Software Engineering, Tongji University, Shanghai, China.
Pengfei YaoSchool of Software Engineering, Tongji University, Shanghai, China.
Antonio Di NarzoDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Yuan ShenDepartment of Psychiatry, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Jing YuDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Yuanyuan LiKey Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Shunqing XuKey Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Jia ChenDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lihong FanDepartment of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Jianwei LuSchool of Software Engineering, Tongji University, Shanghai, China.
Jingkun JiangSchool of Environment, Tsinghua University, Beijing, China.
Yang ZhouSchool of Life Sciences, Tongji University, Shanghai, China.
Changhui WangDepartment of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Zhongyang ZhangDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: zhongyang.zhang@mssm.edu.
Ke HaoDepartment of Respiratory Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China; College of Environmental Science and Engineering, Tongji University, Shanghai, China; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: ke.hao@mssm.edu.

Funding

Placental Functional Networks Linking Developmental Pesticide Exposure and Offspring NeurodevelopmentR01ES029212 · NIEHS · EMORY UNIVERSITY · PI CAUDLE, WILLIAM MICHAEL, CHEN, JIA · 2018 to 2022
$2.7M
NIEHS NIH HHS R01 ES029212
6 · The paper itself

Abstract

backgroundAmbient particulate matter (PM) exposure has been associated with respiratory function decline in epidemiological studies. We hypothesize that a possible underlying mechanism is the perturbation of airway microbiome by PM exposure.

methodsDuring October 2016-October 2017, on two human cohorts (n = 115 in total) in Shanghai China, we systematically collected three categories of data: (1) respiratory functions, (2) airway microbiome from sputum, and (3) PM

resultsThe respiratory function of our primary interest includes forced vital capacity (FVC) and forced expiratory volume in 1st second (FEV

conclusionsTo our knowledge, for the first time, we demonstrated the impact of PM

Indexed as

AdultAgedAir PollutantsChinaCohort StudiesEnvironmental ExposureFemaleForced Expiratory VolumeHumansLungMaleMicrobiotaMiddle AgedParticulate MatterRespirationRespiratory Function TestsAir PollutantsParticulate MatterRNA, Ribosomal, 16SAirway microbiomeAmbient particulate matter (PM) exposureChronic obstructive pulmonary disease (COPD)Next generation sequencingRespiratory functions

Identifiers

PMID30342360
PMCPMC6257984

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.