Evidence map›Paper›PMID 30341956›Full record

ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2019

Prescreening for Osteoporosis With Quantitative Ultrasound in Postmenopausal White Women.

Bernhard Steiner, Hans Peter Dimai, Hubert Steiner, Sabrina Cirar, Astrid Fahrleitner-Pammer

Abstract readEvaluation Study
In one paragraph

Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  5. Development of Artificial Intelligence-Assisted Lumbar and Femoral BMD Estimation System Using Anteroposterior Lumbar X-Ray Images.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bernhard SteinerDepartment of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Hans Peter DimaiDepartment of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Hubert SteinerOG-Ost Apparategemeinschaft Osteoporose St Peter, Graz, Austria.
Sabrina CirarOG-Ost Apparategemeinschaft Osteoporose St Peter, Graz, Austria.
Astrid Fahrleitner-PammerDepartment of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCalcaneal quantitative ultrasound (QUS) is a readily accessible and radiation-free alternative to dual-energy x-ray absorptiometry (DXA) for assessing bone mineral density (BMD). Results obtained from QUS measurement cannot directly be compared to DXA, since these techniques capture different bone-specific parameters. To identify individuals who are likely to have osteoporosis by DXA, device-specific thresholds have to be defined for QUS. This cross-sectional study evaluated the accuracy of QUS to identify postmenopausal women with osteoporosis, defined as a T score of -2.5 SDs or lower by DXA, and to calculate device-specific cutoff values for the QUS device investigated.

methodsWe assessed BMD at the lumbar spine, bilateral femoral neck, and total hip sites with DXA and QUS parameters of the right and left calcanei in a cohort of 245 postmenopausal treatment-naïve women between 40 and 82 years. Correlation coefficients for BMD and QUS parameters were calculated. Receiver operating characteristic curves were generated, and areas under the curves (AUCs) were evaluated. Cutoff values for QUS were defined.

resultsCalcaneal QUS had the ability to identify postmenopausal women with a T score of -2.5 or lower at the right hip (AUC, 0.887) and left femoral neck (AUC, 0.824). Cutoff values for the QUS T scores at the right (-1.455) and left (-1.480) calcanei were defined for screening purposes.

conclusionsThis study provides insights into the comparative performance of QUS with DXA. Considering the diagnostic accuracy of this modality in comparison to DXA, it can be recommended as a prescreening tool to reduce the number of DXA screenings.

Indexed as

AdultAgedAged, 80 and overBone DensityCross-Sectional StudiesEvaluation Studies as TopicFemaleHumansMiddle AgedOsteoporosisPostmenopauseReproducibility of ResultsSensitivity and SpecificityUltrasonographyWhite Peoplebone mineral densitydual-energy x-ray absorptiometryosteoporosispostmenopausal womenprescreeningquantitative ultrasound

Identifiers

PMID30341956
PMCPMC7379566

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.