Evidence map›Paper›PMID 30341761›Full record

ArticleEnvironmental science and pollution research international2018

Protective role of jaboticaba Plinia peruviana peel extract in copper-induced cytotoxicity in Allium cepa.

Francini Franscescon, Samara C Mazon, Kanandra T Bertoncello, Aline A Boligon, Adrieli Sachett, Cassiano L Rambo, Denis B Rosemberg, Jacir Dal Magro, Anna M Siebel

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In one paragraph

Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Francini FranscesconLaboratory of Genetics and Molecular Ecotoxicology, Universidade Comunitária da Região de Chapecó, Chapecó, SC, Brazil.
Samara C MazonLaboratory of Genetics and Molecular Ecotoxicology, Universidade Comunitária da Região de Chapecó, Chapecó, SC, Brazil.
Kanandra T BertoncelloLaboratory of Genetics and Molecular Ecotoxicology, Universidade Comunitária da Região de Chapecó, Chapecó, SC, Brazil.
Aline A BoligonPhytochemical Research Laboratory, Department of Industrial Pharmacy, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Adrieli SachettLaboratory of Genetics and Molecular Ecotoxicology, Universidade Comunitária da Região de Chapecó, Chapecó, SC, Brazil.
Cassiano L RamboLaboratory of Genetics and Molecular Ecotoxicology, Universidade Comunitária da Região de Chapecó, Chapecó, SC, Brazil.
Denis B RosembergLaboratory of Genetics and Molecular Ecotoxicology, Universidade Comunitária da Região de Chapecó, Chapecó, SC, Brazil.
Jacir Dal MagroLaboratory of Genetics and Molecular Ecotoxicology, Universidade Comunitária da Região de Chapecó, Chapecó, SC, Brazil.
Anna M SiebelLaboratory of Genetics and Molecular Ecotoxicology, Universidade Comunitária da Região de Chapecó, Chapecó, SC, Brazil. anna.siebel@unochapeco.edu.br.ORCID http://orcid.org/0000-0002-7896-1456
Community University of Chapecó Region - Unochapecó · BRUniversidade Federal de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jaboticaba Plinia peruviana (Poir.) Govaerts is a Brazilian berry that presents high levels of polyphenols, which may play a key role in preventing cytotoxic and genotoxic effects of harmful agents. Although copper is an essential micronutrient that plays an important role in organisms, high copper concentrations may trigger toxicity to animals and plants. Here, we investigated whether Plinia peruviana hydroalcoholic extract prevents copper-induced cytotoxicity in Allium cepa root cells. Five different anthocyanins and phenolic compounds were identified in Plinia peruviana extract. Importantly, the exposure to 1.53 mg/L copper for 24 h impaired mitotic index, as well as increased mitosis disturbances and triggered DNA damage. Pre-incubation with Plinia peruviana extract (0.25 g/L and 0.75 g/L) for 3 h prevented copper-induced changes in the mitotic index and reduced the number of abnormal cells. In conclusion, we suggest that Plinia peruviana peel extract has protective effects against cellular and genetic disturbances induced by copper.

Indexed as

AnimalsAnthocyaninsBrazilCopperDNA DamageEnvironmental PollutantsFruitMitotic IndexModels, TheoreticalMyrtaceaeOnionsPlant ExtractsPolyphenolsAnthocyaninsCopperEnvironmental PollutantsPlant ExtractsPolyphenolsAnthocyaninsCopper toxicityDNA damageMitotic indexPolyphenolsProtection

Identifiers

PMID30341761
OpenAlexW2896436140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.