Evidence map›Paper›PMID 30341744›Full record

ArticleIntensive care medicine experimental2018

Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart.

Tamara Merz, Britta Lukaschewski, Daniela Wigger, Aileen Rupprecht, Martin Wepler, Michael Gröger, Clair Hartmann, Matthew Whiteman, Csaba Szabo, Rui Wang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Intensive care medicine experimental, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  8. HBiomolecules · 2022
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. HJournal of clinical medicine · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 5 countries.

Tamara MerzInstitute of Anesthesiological Pathophysiology and Process Engineering, University Medical School, Helmholtzstrasse 8-1, 89081, Ulm, Germany. tamara.merz@uni-ulm.de.ORCID http://orcid.org/0000-0002-5519-9171
Britta LukaschewskiInstitute of Anesthesiological Pathophysiology and Process Engineering, University Medical School, Helmholtzstrasse 8-1, 89081, Ulm, Germany.
Daniela WiggerClinic for Psychsomatic Medicine and Psychotherapy, University Medical Center, Ulm, Germany.
Aileen RupprechtInstitute of Anesthesiological Pathophysiology and Process Engineering, University Medical School, Helmholtzstrasse 8-1, 89081, Ulm, Germany.
Martin WeplerInstitute of Anesthesiological Pathophysiology and Process Engineering, University Medical School, Helmholtzstrasse 8-1, 89081, Ulm, Germany.
Michael GrögerInstitute of Anesthesiological Pathophysiology and Process Engineering, University Medical School, Helmholtzstrasse 8-1, 89081, Ulm, Germany.
Clair HartmannInstitute of Anesthesiological Pathophysiology and Process Engineering, University Medical School, Helmholtzstrasse 8-1, 89081, Ulm, Germany.
Matthew WhitemanUniversity of Exeter Medical School, St. Luke's Campus, Exeter, England, UK.
Csaba SzaboChair of Pharmacology, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
Rui WangDepartment of Biology, Laurentian University, Sudbury, ON, Canada.
Christiane WallerClinic for Psychsomatic Medicine and Psychotherapy, University Medical Center, Ulm, Germany.
Peter RadermacherInstitute of Anesthesiological Pathophysiology and Process Engineering, University Medical School, Helmholtzstrasse 8-1, 89081, Ulm, Germany.
Oscar McCookInstitute of Anesthesiological Pathophysiology and Process Engineering, University Medical School, Helmholtzstrasse 8-1, 89081, Ulm, Germany.
Helmholtz-Institute Ulm · DELaurentian University · CANuremberg Hospital · DEUniversity Hospital Ulm · DEUniversity of Exeter · GBUniversity of Fribourg · CH

Funding

Deutsche Forschungsgemeinschaft CRC1149Deutsche Forschungsgemeinschaft CRC1149 GEROKDeutsche Forschungsgemeinschaft IGradUMedical Research Council MC_PC_15047Universität Ulm Hertha-Narthorff-Programm
6 · The paper itself

Abstract

backgroundBoth the hydrogen sulfide/cystathionine-γ-lyase (H

methodsThis study is a post hoc analysis of material obtained in wild type (WT) homozygous CSE

resultsCSE

conclusionsThis study suggests that cardiac CSE regulates cardiac OTR expression, and this effect might play a role in the regulation of cardiovascular function.

Indexed as

Arginine-vasopressin receptorBlood glucoseCardiovascular systemCystathionine-γ-lyaseGYY4137Vascular endothelial growth factor

Identifiers

PMID30341744
PMCPMC6195501
OpenAlexW2896983799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.