Evidence map›Paper›PMID 30341743›Full record

ArticleBrain structure & function2019

Deficiency of the clock gene Bmal1 affects neural progenitor cell migration.

Amira A H Ali, Beryl Schwarz-Herzke, Shakila Mir, Benita Sahlender, Marion Victor, Boris Görg, Martin Schmuck, Katharina Dach, Ellen Fritsche, Andreas Kremer and 1 more

Open access · hybridAbstract readVideo-Audio Media
In one paragraph

Article in Brain structure & function, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. bioRxiv : the preprint server for biology · 2026
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  7. Circadian clock protein BMAL1 broadly influences autophagy and endolysosomal function in astrocytes.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Amira A H AliInstitute of Anatomy II, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Beryl Schwarz-HerzkeInstitute of Anatomy II, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.ORCID http://orcid.org/0000-0002-7210-850X
Shakila MirInstitute of Anatomy II, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Benita SahlenderInstitute of Anatomy II, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Marion VictorInstitute of Anatomy II, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Boris GörgClinic for Gastroenterology, Hepatology and Infectiology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Martin SchmuckLeibniz Research Institute for Environmental Medicine, Modern Risk Assessment and Sphere Biology Group, Auf'm Hennekamp 50, 40225, Düsseldorf, Germany.
Katharina DachLeibniz Research Institute for Environmental Medicine, Modern Risk Assessment and Sphere Biology Group, Auf'm Hennekamp 50, 40225, Düsseldorf, Germany.
Ellen FritscheLeibniz Research Institute for Environmental Medicine, Modern Risk Assessment and Sphere Biology Group, Auf'm Hennekamp 50, 40225, Düsseldorf, Germany.
Andreas KremerDepartment of Bioinformatics, Erasmus University Medical Center Rotterdam, 3015CN, Rotterdam, The Netherlands.
Charlotte von GallInstitute of Anatomy II, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany. charlotte.vongall@med.uni-duesseldorf.de.
Heinrich Heine University Düsseldorf · DELeibniz Institute of Environmental Medicine · DEErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrate the impact of a disrupted molecular clock in Bmal1-deficient (Bmal1

Indexed as

Cell MovementNeurogenesisAnimalsARNTL Transcription FactorsCatalaseCells, CulturedCofilin 1Gene Expression Regulation, DevelopmentalGenotypeMaleMice, Inbred C57BLMice, KnockoutNeural Stem CellsOlfactory BulbOxidative StressPhenotypeARNTL Transcription FactorsBmal1 protein, mouseCatalaseCfl1 protein, mouseCofilin 1Reactive Oxygen SpeciesBmal1CatalaseCircadianClock genesCytoskeletonFilopodiaHydrogen peroxidep-CofilinRNA oxidationRostral migratory streamSubventricular zone

Identifiers

PMID30341743
PMCPMC6373387
OpenAlexW2897858225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.