Evidence map›Paper›PMID 30341740›Full record

ArticleAnnals of biomedical engineering2019

Fecobionics: A Novel Bionics Device for Studying Defecation.

Daming Sun, Zhiyong Huang, Zhuoli Zhuang, Zhiyao Ma, Lo Kar Man, Donghua Liao, Hans Gregersen

Open access · goldAbstract read
In one paragraph

Article in Annals of biomedical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Novel Fecobionics Defecatory Function Testing.Clinical and translational gastroenterology · 2019
    Trial
  3. Observational
  4. Article
  5. Review
  6. Consistency of Feces Affects Defecatory Function.Journal of neurogastroenterology and motility · 2024
    Article
  7. Physiology of lower gastrointestinal tract.Alimentary pharmacology & therapeutics · 2024
    Review
  8. Article
  9. Fecobionics in proctology: review and perspectives.Surgery open digestive advance · 2023
    Article
  10. Article
  11. Article
  12. Novel functional endoscopy for visualization of the anorectal junction and anal canal.Techniques and innovations in gastrointestinal endoscopy · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Daming SunCollege of Communication Engineering, Chongqing University, Shapingba, Chongqing, 400044, China.
Zhiyong HuangCollege of Communication Engineering, Chongqing University, Shapingba, Chongqing, 400044, China. zyhuang@cqu.edu.cn.
Zhuoli ZhuangGIOME, Department of Surgery Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.
Zhiyao MaGIOME, Department of Surgery Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.
Lo Kar ManGIOME DB, Discovery Bay, Hong Kong, Hong Kong.
Donghua LiaoGIOME Academia, Clinical Medicine, Aarhus University, Aarhus, Denmark.
Hans GregersenGIOME, Department of Surgery Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong. hag@giome.org.
Chongqing University · CNPrince of Wales Hospital · CNAarhus University · DKCalifornia Medical Innovations Institute · USNanoBioImaging (China) · CN

Funding

Novel Fecobionics Device for Diagnosis of Anorectal DisordersR43DK112543 · NIDDK · 3DT HOLDINGS, LLC · PI COMBS, WILLIAM, GREGERSEN, HANS · 2017 to 2017
$259k
NIDDK NIH HHS R43 DK112543
6 · The paper itself

Abstract

During defecation, solid, semisolid or liquid stools are eliminated via the anus in a complex physiological process. Up to 25% of the population are affected by anorectal disorders that are poorly recognized and treated. We developed a new bionics device, a simulated stool named Fecobionics, to replace several current tests of anorectal function. Fecobionics was developed to simulate the defecation process that depends on rectal forces, the anorectal size angle, and anorectal size and sensitivity. Fecobionics provided axial pressure signatures, measurement of bending (anorectal angle) and geometric mapping in a single examination. It had the consistency and shape of normal stool. The device had a soft core with embedded electronics and a bag for distension. The paper describes the device development and validation. Furthermore, data were obtained in preliminary experiments in pigs, healthy human subjects and patients with focus on four important features of the system, i.e. measurements of pressure signatures, bending characteristics, impedance measurements and data transmission. Accurate pressure and orientation data as well as geometric profiles were successfully obtained on the bench as well as in vivo in pigs and human subjects during defecation. Fecobionics is a novel technology imitating defecation. The clinical future ultimately depends on its ability to impact on daily treatment of anorectal disorders. A potential long-term clinical application is use of the device for biofeedback training for dyssynergic defecation.

Indexed as

DefecationDiagnostic EquipmentAnal CanalBionicsHumansRectumAnal sphincter relaxationAnorectal physiologyBionicsDefecationFecobionics

Identifiers

PMID30341740
PMCPMC6344295
OpenAlexW2897630694

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.