Evidence map›Paper›PMID 30341736›Full record

ArticleAnnals of biomedical engineering2019

Novel In Vitro Test Systems and Insights for Transcatheter Mitral Valve Design, Part II: Radial Expansion Forces.

Eric L Pierce, Keshav Kohli, Beatrice Ncho, Vahid Sadri, Charles H Bloodworth, Fiona E Mangan, Ajit P Yoganathan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of biomedical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Eric L PierceWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313, USA.
Keshav KohliWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313, USA.
Beatrice NchoWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313, USA.
Vahid SadriWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313, USA.
Charles H BloodworthWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313, USA.
Fiona E ManganWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313, USA.
Ajit P YoganathanWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313, USA. ajit.yoganathan@bme.gatech.edu.ORCID http://orcid.org/0000-0001-5818-1316
Georgia Institute of Technology · US

Funding

Echocardiography to Predict Recurrent IMR After Surgical Mitral Valve ReplacementR01HL103723 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GORMAN, ROBERT C, HUNG, JUDY W · 2011 to 2020
$5.3M
Optimized Mitral AnnuloplastyR01HL147256 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DASI, LAKSHMI PRASAD, GORMAN, ROBERT C · 2019 to 2022
$3.1M
Quantitative Force Measurements to Optimize Valve Repair for Ischemic MRR01HL113216 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GORMAN, JOSEPH H, YOGANATHAN, AJIT P · 2013 to 2016
$2.9M
NHLBI NIH HHS R01 HL103723NHLBI NIH HHS R01 HL113216NHLBI NIH HHS R01 HL147256
6 · The paper itself

Abstract

Transcatheter mitral valve (TMV) replacement technology has great clinical potential for surgically inoperable patients suffering from mitral regurgitation. An important goal for robust TMV design is maximizing the likelihood of achieving a geometry post-implant that facilitates optimal performance. To support this goal, improved understanding of the annular forces that oppose TMV radial expansion is necessary. In Part II of this study, novel circular and D-shaped Radial Expansion Force Transducers (C-REFT and D-REFT) were developed and employed in porcine hearts (N = 12), to detect the forces required to radially expand the mitral annulus to discrete oversizing levels. Forces on both the septal-lateral and inter-commissural axes (F

Indexed as

Heart Valve ProsthesisMitral ValvePostoperative ComplicationsStress, MechanicalTranscatheter Aortic Valve ReplacementAnimalsSwineDevice-tissue interactionForcesIn vitroMedical deviceMitral valveSensorTranscatheterTranscatheter mitral valve implantationTranscatheter mitral valve replacementTransducer

Identifiers

PMID30341736
PMCPMC6520998
OpenAlexW2896886027

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.