Evidence map›Paper›PMID 30341564›Full record

ArticleExtremophiles : life under extreme conditions2019

Behavior of the extremophile green alga Coccomyxa melkonianii SCCA 048 in terms of lipids production and morphology at different pH values.

Santina Soru, Veronica Malavasi, Pierluigi Caboni, Alessandro Concas, Giacomo Cao

Abstract read
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In one paragraph

Article in Extremophiles : life under extreme conditions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Phylogeny and fatty acid profiles of newFrontiers in microbiology · 2025
    Article
  2. Review
  3. Cultivation ofLife (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Metabolomics and lipid profile analysis of Coccomyxa melkonianii SCCA 048.Extremophiles : life under extreme conditions · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Santina SoruInterdepartmental Center of Environmental Science and Engineering (CINSA), University of Cagliari, Via San Giorgio 12, 09124, Cagliari, Italy.
Veronica MalavasiInterdepartmental Center of Environmental Science and Engineering (CINSA), University of Cagliari, Via San Giorgio 12, 09124, Cagliari, Italy. veronica.malavasi@unica.it.ORCID http://orcid.org/0000-0003-3270-2261
Pierluigi CaboniDepartment of Life and Environmental Sciences, University of Cagliari, Via Ospedale 72, 09124, Cagliari, Italy.
Alessandro ConcasCenter for Advanced Studies, Research and Development in Sardinia (CRS4), Loc. Piscina Manna, Building 1, Pula, 09010, Cagliari, Italy.
Giacomo CaoInterdepartmental Center of Environmental Science and Engineering (CINSA), University of Cagliari, Via San Giorgio 12, 09124, Cagliari, Italy.

Funding

COMISAR project POR FESR 2014/2020 - Asse prioritario I "ricerca
6 · The paper itself

Abstract

The extremophile green alga Coccomyxa melkonianii SCCA 048 was investigated to evaluate its ability to grow in culture media with different pH. Specifically, Coccomyxa melkonianii was sampled in the Rio Irvi river (Sardinia, Italy) which is severely polluted by heavy metals as a result of abandoned mining activities. In this study, the strain was cultivated in growth media where the pH was kept fixed at the values of 4.0, 6.8 and 8.0, respectively. During the investigation, a significant phenotypic plasticity of this strain was observed. The strain grew well in the pH range 4.0-8.0, while the optimal value for its growth was 6.8. Furthermore, maximum lipid contents of about 24 and 22 %wt were achieved at the end of cultivation when using pH 4.0 and 8.0, respectively. Finally, the analysis of fatty acid methyl esters (FAMEs) highlights the presence of suitable amounts of compounds which can be profitably exploited in the food, nutraceutical, and cosmetic industry. This aspect, coupled with the possibility of cultivating Coccomyxa melkonianii under extreme pH conditions in economic open ponds, makes this strain an interesting candidate for several biotechnological applications.

Indexed as

ChlorophytaFatty AcidsHydrogen-Ion ConcentrationThermotoleranceFatty AcidsCoccomyxa melkonianii SCCA 048Extremophile algaeFatty acidsMorphologypH response

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.