Evidence map›Paper›PMID 30341456›Full record

ReviewWorld journal of microbiology & biotechnology2018

Understanding and engineering alcohol-tolerant bacteria using OMICS technology.

Takaaki Horinouchi, Tomoya Maeda, Chikara Furusawa

Abstract readReview
In one paragraph

Review in World journal of microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Enhanced growth of 1-butanol producingBiodesign research · 2026
    Article
  2. Review
  3. Cellulolytic Potential of Newly Isolated Alcohol-TolerantMaterials (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Engineering robust microorganisms for organic acid production.Journal of industrial microbiology & biotechnology · 2022
    Review
  11. Role of peptidoglycan recycling enzymes AmpD and AnmK inFrontiers in cellular and infection microbiology · 2022
    Article
  12. Role of Iron-Containing Alcohol Dehydrogenases inInternational journal of molecular sciences · 2021
    Article
  13. Article
  14. Review
  15. Omics-Driven Biotechnology for Industrial Applications.Frontiers in bioengineering and biotechnology · 2021
    Review
  16. Review
  17. Article
  18. Article
  19. A Novel Butanol Tolerance-Promoting Function of the Transcription Factor Rob inFrontiers in bioengineering and biotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Takaaki HorinouchiCenter for Biosystems Dynamics Research (BDR), RIKEN, 6-2-3 Furuedai, Suita, Osaka, 565-0874, Japan. takaaki_horinouchi@riken.jp.ORCID http://orcid.org/0000-0001-9141-9103
Tomoya MaedaCenter for Biosystems Dynamics Research (BDR), RIKEN, 6-2-3 Furuedai, Suita, Osaka, 565-0874, Japan.
Chikara FurusawaCenter for Biosystems Dynamics Research (BDR), RIKEN, 6-2-3 Furuedai, Suita, Osaka, 565-0874, Japan. chikara.furusawa@riken.jp.

Funding

Japan Society for the Promotion of Science JP17K15052Japan Society for the Promotion of Science JP18H04807
6 · The paper itself

Abstract

Microbes are capable of producing alcohols, making them an important source of alternative energy that can replace fossil fuels. However, these alcohols can be toxic to the microbes themselves, retaring or inhibiting cell growth and decreasing the production yield. One solution is improving the alcohol tolerance of such alcohol-producing organisms. Advances in omics technologies, including transcriptomic, proteomic, metabolomic, and genomic technologies, have helped us understand the complex mechanisms underlying alcohol toxicity, and such advances could assist in devising strategies for engineering alcohol-tolerant strains. This review highlights these advances and discusses strategies for improving alcohol tolerance using omics analyses.

Indexed as

Drug ToleranceAdaptation, BiologicalAlcoholsBacteriaBacterial Physiological PhenomenaEthanolGenomicsMetabolic EngineeringMetabolomicsProteomicsAlcoholsEthanolAdaptive laboratory evolutionAlcohol toleranceBacteriaOmics technology

Identifiers

PMID30341456
PMCPMC6208762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.