ArticleProceedings of the National Academy of Sciences of the United States of America2018
Multiscale effects of heating and cooling on genes and gene networks.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 56 citations in OpenAlex.
- Multiscale learning of gene network-driven phenotypic dynamics of single cells.Molecular systems biology · 2026Article
- Mechanistic origins of temperature scaling in the early embryonic cell cycle.Nature communications · 2025Article
- Stimuli-responsive hybrid materials for 4DMaterials today. Bio · 2025Review
- Imaging-Guided Microscale Photothermal Stereolithography Bioprinting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Bimodality in E. coli gene expression: Sources and robustness to genome-wide stresses.PLoS computational biology · 2025Article
- Synthetic gene circuit evolution: Insights and opportunities at the mid-scale.Cell chemical biology · 2024Review
- LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae.Nucleic acids research · 2024Article
- Microbial life in slow and stopped lanes.Trends in microbiology · 2024Review
- Dynamical model of antibiotic responses linking expression of resistance genes to metabolism explains emergence of heterogeneity during drug exposures.Physical biology · 2024Article
- The multiple activations in budding yeast S-phase checkpoint are Poisson processes.PNAS nexus · 2023Article
- Analysis of acid-tolerance mechanism based on membrane microdomains in Saccharomyces cerevisiae.Microbial cell factories · 2023Article
- Identification and Elimination of Antifungal Tolerance inBiomedicines · 2023Article
- The potential of cold-shock promoters for the expression of recombinant proteins in microbes and mammalian cells.Journal, genetic engineering & biotechnology · 2022Review
- Time-resolved microfluidics unravels individual cellular fates during double-strand break repair.BMC biology · 2022Article
- Alteration of DNA supercoiling serves as a trigger of short-term cold shock repressed genes of E. coli.Nucleic acids research · 2022Article
- Using single-cell models to predict the functionality of synthetic circuits at the population scale.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Single-Cell Microgels for Diagnostics and Therapeutics.Advanced functional materials · 2021Article
- Emergent Damped Oscillation Induced by Nutrient-Modulating Growth Feedback.ACS synthetic biology · 2021Article
- Yeasts collectively extend the limits of habitable temperatures by secreting glutathione.Nature microbiology · 2020Article
- How Do Cells Adapt? Stories Told in Landscapes.Annual review of chemical and biomolecular engineering · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Most organisms must cope with temperature changes. This involves genes and gene networks both as subjects and agents of cellular protection, creating difficulties in understanding. Here, we study how heating and cooling affect expression of single genes and synthetic gene circuits in
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.