Evidence map›Paper›PMID 30341178›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

FABP3 in the Anterior Cingulate Cortex Modulates the Methylation Status of the Glutamic Acid Decarboxylase

Yui Yamamoto, Hiroyuki Kida, Yoshiteru Kagawa, Yuki Yasumoto, Hirofumi Miyazaki, Ariful Islam, Masaki Ogata, Yuchio Yanagawa, Dai Mitsushima, Kohji Fukunaga and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

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  19. Genetic polymorphism and neuroanatomical changes in schizophrenia.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yui YamamotoDepartment of Organ Anatomy, Tohoku University, Sendai 980-8575, Japan, owada@med.tohoku.ac.jp yuiyama@tohoku-mpu.ac.jp.
Hiroyuki KidaDepartment of System Neuroscience, Yamaguchi University, Ube 755-8505, Japan.
Yoshiteru KagawaDepartment of Organ Anatomy, Tohoku University, Sendai 980-8575, Japan.
Yuki YasumotoDepartment of Organ Anatomy, Tohoku University, Sendai 980-8575, Japan.
Hirofumi MiyazakiDepartment of Organ Anatomy, Tohoku University, Sendai 980-8575, Japan.
Ariful IslamDepartment of Organ Anatomy, Tohoku University, Sendai 980-8575, Japan.
Masaki OgataDepartment of Organ Anatomy, Tohoku University, Sendai 980-8575, Japan.
Yuchio YanagawaDepartment of Genetic and Behavioural Neuroscience, Gunma University, Maebashi 371-8511, Japan, and.
Dai MitsushimaDepartment of System Neuroscience, Yamaguchi University, Ube 755-8505, Japan.ORCID 0000-0002-6931-7714
Kohji FukunagaDepartment of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Yuji OwadaDepartment of Organ Anatomy, Tohoku University, Sendai 980-8575, Japan, owada@med.tohoku.ac.jp yuiyama@tohoku-mpu.ac.jp.
Tohoku University · JPYamaguchi University · JPGunma University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyunsaturated fatty acids (PUFAs) are essential for brain development and function. Increasing evidence has shown that an imbalance of PUFAs is associated with various human psychiatric disorders, including autism and schizophrenia. Fatty acid-binding proteins (FABPs), cellular chaperones of PUFAs, are involved in PUFA intracellular trafficking, signal transduction, and gene transcription. In this study, we show that FABP3 is strongly expressed in the GABAergic inhibitory interneurons of the male mouse anterior cingulate cortex (ACC), which is a component of the limbic cortex and is important for the coordination of cognitive and emotional behaviors. Interestingly,

Indexed as

AnimalsCell Line, TumorDNA MethylationFatty Acid Binding Protein 3Glutamate DecarboxylaseGyrus CinguliMaleMiceMice, Inbred C57BLMice, KnockoutOrgan Culture TechniquesPromoter Regions, GeneticFabp3 protein, mouseFatty Acid Binding Protein 3Glutamate Decarboxylaseglutamate decarboxylase 1ACCFABP3GABAGAD67parvalbuminPUFA

Identifiers

PMID30341178
PMCPMC6596254
OpenAlexW2897272839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.