Evidence map›Paper›PMID 30341174›Full record

ArticleThe Journal of biological chemistry2018

The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg

Yu Seby Chen, Guennadi Kozlov, Rayan Fakih, Yosuke Funato, Hiroaki Miki, Kalle Gehring

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Novel mutation inInternational journal of ophthalmology · 2025
    Article
  5. Article
  6. Article
  7. Dimerization of the CNNM extracellular domain.Protein science : a publication of the Protein Society · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. NovelFrontiers in genetics · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Structural basis for the MgScience advances · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yu Seby ChenFrom the Department of Biochemistry and Centre for Structural Biology, McGill University, Montreal, Quebec H3G 0B1, Canada and.
Guennadi KozlovFrom the Department of Biochemistry and Centre for Structural Biology, McGill University, Montreal, Quebec H3G 0B1, Canada and.
Rayan FakihFrom the Department of Biochemistry and Centre for Structural Biology, McGill University, Montreal, Quebec H3G 0B1, Canada and.
Yosuke Funatothe Department of Cellular Regulation, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.
Hiroaki Mikithe Department of Cellular Regulation, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.
Kalle GehringFrom the Department of Biochemistry and Centre for Structural Biology, McGill University, Montreal, Quebec H3G 0B1, Canada and. Electronic address: kalle.gehring@mcgill.ca.
McGill University · CAThe University of Osaka · JP

Funding

ZINC FINGER-DNA COMPLEXP41RR001646 · NCRR · CORNELL UNIVERSITY ITHACA · PI ROSE, ROBERT C · 1985 to 2011
$23.8M
NCRR NIH HHS P41 RR001646NIGMS NIH HHS DMR-0225180
6 · The paper itself

Abstract

Proteins of the cyclin M family (CNNMs; also called ancient conserved domain proteins, or ACDPs) are represented by four integral membrane proteins that have been proposed to function as Mg

Indexed as

Amino Acid SequenceCation Transport ProteinsCrystallography, X-RayCyclinsHumansMagnesiumModels, MolecularMolecular Docking SimulationProtein BindingProtein ConformationProtein DomainsProtein MultimerizationCation Transport ProteinsCNNM2 protein, humanCNNM3 protein, humanCyclinsMagnesiumanalytical ultracentrifugationbiophysicsCNNMcrystal structurecyclic nucleotide-binding homology domaindimerizationmagnesiumstructural biologytransporterX-ray crystallography

Identifiers

PMID30341174
PMCPMC6311497
OpenAlexW2896212932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.