Trial reportPediatrics2018
Advance Care Planning and HIV Symptoms in Adolescence.
Trial report in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01289444 (Longitudinal Pediatric Palliative Care), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Longitudinal Pediatric Palliative Care: Quality of Life & Spiritual Struggle
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- A Dutch paediatric palliative care guideline: a systematic review and recommendations on advance care planning and shared decision-making.BMC palliative care · 2024Pooled it
- Pediatric Advance Care Planning and Adolescent Preparedness and Quality of Life: An RCT.Pediatrics · 2025Trial
- Effect of the Family-Centered Advance Care Planning for Teens with Cancer Intervention on Sustainability of Congruence About End-of-Life Treatment Preferences: A Randomized Clinical Trial.JAMA network open · 2022Trial
- An Intervention in Congruence for End-of-Life Treatment Preference: A Randomized Trial.Pediatrics · 2022Trial
- Pediatric Advance Care Planning and Families' Positive Caregiving Appraisals: An RCT.Pediatrics · 2021Trial
- Effect of FAmily CEntered (FACE®) Advance Care Planning on Longitudinal Congruence in End-of-Life Treatment Preferences: A Randomized Clinical Trial.AIDS and behavior · 2020Trial
- FAmily-CEntered (FACE) Advance Care Planning Among African-American and Non-African-American Adults Living With HIV in Washington, DC: A Randomized Controlled Trial to Increase Documentation and Health Equity.Journal of pain and symptom management · 2019Trial
- Parental Goals of Care for Children With Rare Diseases: A Content Analysis of Pediatric Advance Care Planning Conversations.The American journal of hospice & palliative care · 2026Article
- "The American journal of hospice & palliative care · 2025Article
- Advancing Advance Care Planning: Evaluating a Revised Version of Voicing My CHOiCES.Journal of palliative medicine · 2025Article
- Palliative Care Interventions Among Adolescents and Young Adults with Serious Illness: A Scoping Review.Clinical practice in pediatric psychology · 2023Article
- Interventions to Improve Adolescent HIV Care Outcomes.Current HIV/AIDS reports · 2023Review
- Family caregivers of children and adolescents with rare diseases: a novel palliative care intervention.BMJ supportive & palliative care · 2022Article
- Initiation of paediatric advance care planning: Cross-sectional survey of health professionals reported behaviour.Child: care, health and development · 2022Article
- Family-Centered Advance Care Planning: What Matters Most for Parents of Children with Rare Diseases.Children (Basel, Switzerland) · 2022Article
- Adolescent and Young Adult Initiated Discussions of Advance Care Planning: Family Member, Friend and Health Care Provider Perspectives.Frontiers in psychology · 2022Article
- Providing Palliative and Hospice Care to Children, Adolescents and Young Adults with Cancer.Seminars in oncology nursing · 2021Review
- Weaver et al's Response to Morrison: Advance Directives/Care Planning: Clear, Simple, and Wrong (DOI: 10.1089/jpm.2020.0272).Journal of palliative medicine · 2021Article
- The Effect of FAmily-CEntered (FACEJournal of family nursing · 2020Article
- The influence of religious beliefs and practices on health care decision-making among HIV positive adolescents.AIDS care · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesTo determine the effect of family-centered pediatric advance care planning (FACE pACP) on HIV-specific symptoms.
methodsIn this single-blinded, randomized controlled trial conducted at 6 US hospital-based HIV clinics, 105 adolescent-family dyads, randomly assigned from July 2011 to June 2014, received 3 weekly sessions in either the FACE pACP arm ([1] pediatric advance care planning survey, [2] Respecting Choices interview, and [3] 5 Wishes directive) or the control arm ([1] developmental history, [2] safety tips, and [3] nutrition and exercise tips). The General Health Assessment for Children measured patient-reported HIV-specific symptoms. Latent class analyses clustered individual patients based on symptom patterns. Path analysis examined the mediating role of dyadic treatment congruence with respect to the intervention effect on symptom patterns.
resultsPatients were a mean age of 17.8 years old, 54% male, and 93% African American. Latent class analysis identified 2 latent HIV-symptom classes at 12 months: higher symptoms and suffering (27%) and lower symptoms and suffering (73%). FACE pACP had a positive effect on dyadic treatment congruence (β = .65; 95% CI: 0.04 to 1.28), and higher treatment congruence had a negative effect on symptoms and suffering (β = -1.14; 95% CI: -2.55 to -0.24). Therefore, FACE pACP decreased the likelihood of symptoms and suffering through better dyadic treatment congruence (β = -.69; 95% CI: -2.14 to -0.006). Higher religiousness (β = 2.19; 95% CI: 0.22 to 4.70) predicted symptoms and suffering.
conclusionsFACE pACP increased and maintained agreement about goals of care longitudinally, which lowered adolescents' physical symptoms and suffering, suggesting that early pACP is worthwhile.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.