Evidence map›Paper›PMID 30341137›Full record

ArticleBMJ open2018

Availability, prices and affordability of essential medicines for children: a cross-sectional survey in Jiangsu Province, China.

Xiaoluan Sun, Jing Wei, Yuan Yao, Qiutong Chen, Daiting You, Xinglu Xu, Jing Dai, Yanping Yao, Jingyi Sheng, Xin Li

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  10. Access to medicines for children in China.BMJ paediatrics open · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaoluan SunDepartment of Health Policy, School of Health Policy and Management, Nanjing Medical University, Nanjing, Jiangsu, China.
Jing WeiDepartment of Clinical Pharmacy, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Yuan YaoDepartment of Clinical Pharmacy, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Qiutong ChenDepartment of Clinical Pharmacy, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Daiting YouDepartment of Clinical Pharmacy, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Xinglu XuDepartment of Clinical Pharmacy, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Jing DaiDepartment of Clinical Pharmacy, School of Pharmacy, Nanjing Medical University, Nanjing, China.
Yanping YaoSuzhou Xiangcheng District Health and Family Planning Bureau, Suzhou, China.
Jingyi ShengDepartment of Pediatrics, The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Xin LiDepartment of Health Policy, School of Health Policy and Management, Nanjing Medical University, Nanjing, Jiangsu, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChina has undertaken several initiatives to improve the accessibility of safe and effective medicines for children. The aim was to determine the availability, price and affordability of essential medicines for children.

designCross-sectional survey.

settingSix cities of Jiangsu Province, China.

participants30 public hospitals and 30 retail pharmacies. PRIMARY AND SECONDARY OUTCOME MEASURES: The WHO/Health Action International standardised methodology was used to collect the availability and price data for 40 essential medicines for children. Availability was measured as the percentage of drug outlets per sector where the individual medicine was found on the day of data collection, and prices were measured as median price ratios (MPRs). Affordability was measured as the number of days' wages required for the lowest paid unskilled government worker to purchase standard treatments for common conditions.

resultsThe mean availabilities of originator brands (OBs) and lowest priced generics (LPGs) were 7.5% and 34.2% in the public sector and 8.9% and 29.4% in the private sector. The median MPRs of LPGs in both sectors ranged from 1.41 to 2.12 and 1.10 to 2.24, respectively. However, the patient prices of OBs far exceeded the critical level in both sectors, with median MPRs ranging from 2.47 to 8.22. More than half of these LPGs were priced at 1.5 times their international reference prices in the public sector. Most LPGs were affordable for treatment of common conditions in both public and private sectors, as they each cost less than the daily wage for the lowest paid unskilled government worker.

conclusionsAccess to essential medicines for children is hampered by low availability. Further measures to enhance access to paediatric essential medicines should be taken, such as developing a national essential medicine list for children and mobilising the enthusiasm of pharmaceutical firms to develop and manufacture paediatric medicines.

Indexed as

ChildChinaCommerceCross-Sectional StudiesDrug PrescriptionsDrugs, EssentialDrugs, GenericHealth Services AccessibilityHumansPharmaceutical PreparationsPrivate SectorPublic SectorDrugs, EssentialDrugs, GenericPharmaceutical Preparationsaffordabilityavailabilitychildrenchinaessential medicinesprices

Identifiers

PMID30341137
PMCPMC6196968
OpenAlexW2896749075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.