Evidence map›Paper›PMID 30341129›Full record

ArticleBMJ open2018

Influence of family history on prognosis of spinal pain and the role of leisure time physical activity and body mass index: a prospective study using family-linkage data from the Norwegian HUNT study.

Anita B Amorim, Paulo H Ferreira, Manuela L Ferreira, Ragnhild Lier, Milena Simic, Evangelos Pappas, Joshua R Zadro, Paul Jarle Mork, Tom Il Nilsen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Anita B AmorimFaculty of Health Sciences, The University of Sydney, Discipline of Physiotherapy, Sydney, New South Wales, Australia.
Paulo H FerreiraFaculty of Health Sciences, The University of Sydney, Discipline of Physiotherapy, Sydney, New South Wales, Australia.
Manuela L FerreiraInstitute of Bone and Joint Research, The Kolling Institute, Sydney Medical School, Sydney, New South Wales, Australia.
Ragnhild LierDepartment of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.
Milena SimicFaculty of Health Sciences, The University of Sydney, Discipline of Physiotherapy, Sydney, New South Wales, Australia.ORCID 0000-0002-5387-3986
Evangelos PappasFaculty of Health Sciences, The University of Sydney, Discipline of Physiotherapy, Sydney, New South Wales, Australia.
Joshua R ZadroFaculty of Health Sciences, The University of Sydney, Discipline of Physiotherapy, Sydney, New South Wales, Australia.
Paul Jarle MorkDepartment of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.
Tom Il NilsenDepartment of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.
The University of Sydney · AUNorwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the influence of parental chronic spinal pain on prognosis of chronic spinal pain in adult offspring, and whether offspring physical activity level and body mass index (BMI) modified this association.

designProspective cohort study.

settingWe used family-linked longitudinal data from the Norwegian HUNT study collected in HUNT2 (1995-1997) and HUNT3 (2006-2008).

participantsA total of 1529 offspring who reported spinal pain in HUNT2 were linked with parental data and followed up in HUNT3. OUTCOMES: We estimated relative risk (RR) with 95% CI for recovery from chronic spinal pain, and also from activity limiting spinal pain, in offspring related to chronic spinal pain in parents. We also investigated whether offspring leisure time physical activity and BMI modified these intergenerational associations in spinal pain.

resultsA total of 540 (35%) offspring were defined as recovered after approximately 11 years of follow-up. Offspring with both parents reporting chronic spinal pain were less likely to recover from chronic spinal pain (RR 0.83, 95% CI 0.69 to 0.99) and activity limiting spinal pain (RR 0.71, 95% CI 0.54 to 0.94), compared with offspring of parents without chronic spinal pain. Analyses stratified by BMI and physical activity showed no strong evidence of effect modification on these associations. However, offspring who were overweight/obese and with both parents reporting chronic spinal pain had particularly low probability of recovery from activity limiting spinal pain, compared with those who were normal weight and had parents without chronic spinal pain (RR 0.57, 95% CI 0.39 to 0.84).

conclusionOffspring with chronic spinal pain are less likely to recover if they have parents with chronic spinal pain, particularly if offspring are overweight/obese.

Indexed as

Adult ChildrenBody Mass IndexLeisure ActivitiesMedical History TakingParentsAdultAgedBack PainChronic PainFamily HealthFemaleHumansInformation Storage and RetrievalMaleMiddle AgedNorwaychronic painfamily studylow back painneck painobesityphysical activity

Identifiers

PMID30341129
PMCPMC6196861
OpenAlexW2896461985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.