ArticleAIDS research and therapy2018
Risky sexual behavior among patients on long-term antiretroviral therapy: a prospective cohort study in urban and rural Uganda.
Article in AIDS research and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
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- Prevalence and risk factors of high-risk sexual behavior among elderly men with HIV infection in Chongqing, China.Scientific reports · 2025Article
- Psychosocial Phenotype and Risky Sexual Behavior Among People Living with HIV in Changsha: A Latent Profile Analysis.International journal of sexual health : official journal of the World Association for Sexual Health · 2025Article
- Current syphilis infection in virally suppressed people living with HIV: a cross-sectional study in eastern China.Frontiers in public health · 2024Article
- High prevalence of risky sexual behaviour among key populations receiving antiretroviral therapy at a large HIV clinic in northern Uganda.African health sciences · 2023Article
- Nearly half of adults with symptoms of sexually transmitted infections (STIs) did not seek clinical care: A population-based study of treatment-seeking behavior among adults in Rakai, Uganda.PLOS global public health · 2023Article
- Facilitators and barriers to status disclosure and partner testing of women living with HIV in Indonesia: a mixed methods study.Sexual and reproductive health matters · 2022Article
- Is There Risk Compensation among HIV Infected Youth and Adults 15 Years and Older on Antiretroviral Treatment in South Africa? Findings from the 2017 National HIV Prevalence, Incidence, Behaviour and Communication Survey.International journal of environmental research and public health · 2022Article
- Article
- Factors Contributing to High HIV Prevalence in Majang Zone, Southwest Ethiopia: What Lies Beneath the Tip of the Iceberg?Journal of multidisciplinary healthcare · 2021Article
- Socio-behavioural characteristics and HIV: findings from a graphical modelling analysis of 29 sub-Saharan African countries.Journal of the International AIDS Society · 2019Article
- Incidence rate of sexually transmitted infections among HIV infected patients on long-term ART in an urban and a rural clinic in Uganda.BMC public health · 2019Article
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10 authors.
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Abstract
backgroundWhile the effects of initiation of antiretroviral treatment (ART) on risky sexual behavior have been extensively studied, less is known about the long-term changes in risky sexual behavior over time in resource-poor settings.
methodsWe conducted a secondary longitudinal analysis of one rural and one urban cohort of patients who initiated ART in Uganda between April 2004 and July 2007 followed up-to 2016. Data on sexual behavior were collected every 6 months for 3.5 years in individuals on ART ≥ 4 years (baseline) when a behavioral questionnaire was introduced. Risky sexual behavior was defined as sexual intercourse with ≥ 2 partners or inconsistent or no condom use in previous 6 months. We report characteristics overall, and by cohort. We used multivariable generalized estimating equations logistic regression to assess the effects of time on ART on risky sexual behavior.
resultsOf 1012 participants, 402 (39.8%) were urban and 610 (60.2%) were rural residents. Mean age was 42.8 years (SD 8.5). Mean duration of follow-up was 51.3 months (SD 15.3), but longer for urban than rural participants (64.5 vs 36.4 months). Risky sexual behavior declined from 33.1% at baseline to 9.6% after 3.5 years of follow-up in the rural cohort (p ≤ 0.01 for the test of trend) and was unchanged from 9.7% at baseline to 9.9% after 3.5 years in the urban cohort (p = 0.51). Receiving care at a rural clinic (aOR 4.99, 95% CI 3.64-6.84); male gender (aOR 1.66, 95% CI 1.26-2.19) and being younger (aOR 5.60, 95% CI 3.80-8.25 for 18-34 years and aOR 2.34, 95% CI 1.74-3.14 for 35-44 years) were associated with increased odds of risky sexual behavior. Not being married (aOR 0.25; 95% CI 0.19-0.34), and longer time on ART (aOR 0.71 95% CI 0.67-0.76) were associated with reduced odds of risky sex.
conclusionsWe observed a decline in risky sexual behavior in rural people on long-term (≥ 4 years) ART. Rural, male and young individuals had higher odds of self-reported risky sexual behavior. ART programs should continue to emphasize risk reduction practices, especially among people receiving care in rural health facilities, males, younger individuals and those who are married.
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