Evidence map›Paper›PMID 30340567›Full record

ArticleBMC complementary and alternative medicine2018

Hexane extract from Spondias tuberosa (Anacardiaceae) leaves has antioxidant activity and is an anti-Candida agent by causing mitochondrial and lysosomal damages.

Bruna Maria Pereira da Costa Cordeiro, Nataly Diniz de Lima Santos, Magda Rhayanny Assunção Ferreira, Larissa Cardoso Corrêa de Araújo, Alexsander Rodrigues Carvalho Junior, Alan Diego da Conceição Santos, Ana Paula de Oliveira, Alexandre Gomes da Silva, Emerson Peter da Silva Falcão, Maria Tereza Dos Santos Correia and 6 more

Abstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Molecules (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Article
  8. Anti-Fungal Efficacy and Mechanisms of Flavonoids.Antibiotics (Basel, Switzerland) · 2020
    Review
  9. UPLC-MS-ESI-QTOF Analysis and Antifungal Activity of theAntibiotics (Basel, Switzerland) · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Bruna Maria Pereira da Costa CordeiroDepartamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
Nataly Diniz de Lima SantosDepartamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
Magda Rhayanny Assunção FerreiraDepartamento de Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade Federal de Pernambuco, Recife, Pernambuco, 50740-520, Brazil.
Larissa Cardoso Corrêa de AraújoDepartamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
Alexsander Rodrigues Carvalho JuniorUniversidade CEUMA, São Luís, Maranhão, 65075-120, Brazil.
Alan Diego da Conceição SantosNúcleo de Estudos e Pesquisas de Plantas Medicinais, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, 56304-205, Brazil.
Ana Paula de OliveiraNúcleo de Estudos e Pesquisas de Plantas Medicinais, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, 56304-205, Brazil.
Alexandre Gomes da SilvaDepartamento de Antibióticos, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
Emerson Peter da Silva FalcãoNúcleo de Nutrição, Centro Acadêmico de Vitória, Universidade Federal de Pernambuco, Vitória de Santo Antão, Pernambuco, 55608-680, Brazil.
Maria Tereza Dos Santos CorreiaDepartamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
Jackson Roberto Guedes da Silva AlmeidaNúcleo de Estudos e Pesquisas de Plantas Medicinais, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, 56304-205, Brazil.
Luís Cláudio Nascimento da SilvaUniversidade CEUMA, São Luís, Maranhão, 65075-120, Brazil.
Luiz Alberto Lira SoaresDepartamento de Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade Federal de Pernambuco, Recife, Pernambuco, 50740-520, Brazil.
Thiago Henrique NapoleãoDepartamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
Márcia Vanusa da SilvaDepartamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
Patrícia Maria Guedes PaivaDepartamento de Bioquímica, Centro de Biociências, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil. ppaivaufpe@yahoo.com.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 446902/2014-4Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco APQ-0108-2.08/14Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco APQ-0493-4.03/14Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco APQ-0661-2.08/15
6 · The paper itself

Abstract

backgroundSpondias tuberosa is a plant that produces a fruit crop with high economic relevance at Brazilian Caatinga. Its roots and leaves are used in folk medicine.

methodsChemical composition of a hexane extract from S. tuberosa leaves was evaluated by thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC) and

resultsPhytochemical analysis by TLC showed the presence of flavonoids, hydrolysable tannins, saponins and terpenes. The HPLC profile of the extract suggested the presence of gallic acid (0.28 ± 0.01 g%) and hyperoside (1.27 ± 0.01 g%). The representative

conclusionThe results demonstrate the pharmacological potential of the extract as antioxidant and antifungal agent, aggregating biotechnological value to this plant and stimulating its conservation.

Indexed as

AnacardiaceaeAntifungal AgentsAntioxidantsCandidaHexanesLysosomesMitochondrial MembranesPlant ExtractsAntifungal AgentsAntioxidantsHexanesPlant ExtractsAntifungal activityFatty acidsGallic acidHyperosideSpondias tuberosa

Identifiers

PMID30340567
PMCPMC6194709

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.