Evidence map›Paper›PMID 30340565›Full record

ArticleBMC pulmonary medicine2018

Adherence to inhaled therapy and its impact on chronic obstructive pulmonary disease (COPD).

Magdalena Humenberger, Andreas Horner, Anna Labek, Bernhard Kaiser, Rupert Frechinger, Constanze Brock, Petra Lichtenberger, Bernd Lamprecht

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Digital remote maintenance inhaler adherence interventions in COPD: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  3. Pooled it
  4. Methods to assess COPD medications adherence in healthcare databases: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  5. Pooled it
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  15. Quality of Care and Outcomes of Inpatients with COPD: A Multi-Center Study in China.International journal of chronic obstructive pulmonary disease · 2025
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Magdalena HumenbergerDepartment of Pulmonology, Kepler University Hospital, Krankenhausstrasse 9, A4021, Linz, Austria.
Andreas HornerDepartment of Pulmonology, Kepler University Hospital, Krankenhausstrasse 9, A4021, Linz, Austria. Andreas.Horner@kepleruniklinikum.at.ORCID http://orcid.org/0000-0001-7746-3335
Anna LabekDepartment of Health Economics, Upper Austrian Health Insurance, Linz, Austria.
Bernhard KaiserDepartment of Health Economics, Upper Austrian Health Insurance, Linz, Austria.
Rupert FrechingerDepartment of Medical Controlling, Kepler University Hospital, Linz, Austria.
Constanze BrockDepartment of Pulmonology, Kepler University Hospital, Krankenhausstrasse 9, A4021, Linz, Austria.
Petra LichtenbergerDepartment of Pulmonology, Kepler University Hospital, Krankenhausstrasse 9, A4021, Linz, Austria.
Bernd LamprechtDepartment of Pulmonology, Kepler University Hospital, Krankenhausstrasse 9, A4021, Linz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOPD is a treatable disease with increasing prevalence worldwide. Treatment aims to stop disease progression, to improve quality of life, and to reduce exacerbations. We aimed to evaluate the association of the stage of COPD on adherence to inhaled therapy and the relationship between adherence and COPD exacerbations.

methodsA retrospective analysis of patients hospitalized for acute exacerbation of COPD in a tertiary care hospital in Upper Austria and discharged with a guideline conform inhaled therapy was performed. Follow-up data on medical utilization was recorded for the subsequent 24 months. Adherence to inhaled therapy was defined according to the percentage of prescribed inhalers dispensed to the patient and classified as complete (> 80%), partial (50-80%) or low (< 50%).

resultsOut of 357 patients, 65.8% were male with a mean age of 66.5 years and a mean FEV

conclusionComplete adherence to inhaled therapy was only seen in 33.6% and was higher among those with more severe COPD.

trial registrationNot applicable.

Indexed as

Disease ProgressionDrug MonitoringRespiratory TherapyAgedAustriaDrug Therapy, CombinationFemaleForced Expiratory VolumeHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisNebulizers and VaporizersPulmonary Disease, Chronic ObstructiveQuality of LifeAdherenceChronic obstructive pulmonary diseaseInhaled therapy

Identifiers

PMID30340565
PMCPMC6194635

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.