Evidence map›Paper›PMID 30340545›Full record

ReviewBMC nephrology2018

TINU-associated Fanconi syndrome: a case report and review of literature.

Bernard Vô, Jean Cyr Yombi, Selda Aydin, Nathalie Demoulin, Halil Yildiz

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bernard VôDepartment of internal medicine and infectious diseases, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10 Av. Hippocrate, 1200, Brussels, Belgium.
Jean Cyr YombiDepartment of internal medicine and infectious diseases, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10 Av. Hippocrate, 1200, Brussels, Belgium. jean.yombi@uclouvain.be.
Selda AydinDepartment of pathology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10 Av. Hippocrate, 1200, Brussels, Belgium.
Nathalie DemoulinDivision of Nephrology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10 Av. Hippocrate, 1200, Brussels, Belgium.
Halil YildizDepartment of internal medicine and infectious diseases, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10 Av. Hippocrate, 1200, Brussels, Belgium.
Cliniques Universitaires Saint-Luc · BEUCLouvain · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTubulo-interstitial Nephritis and Uveitis (TINU) syndrome is a rare oculo-renal inflammatory disease. Renal tubular defects are usually found, but full proximal tubular abnormalities have rarely been described. CASE PRESENTATION: We report the case of a 55-year old woman, native from Morocco, presenting with bilateral, non-granulomatous, anterior uveitis, mild renal insufficiency, leucocyturia and glycosuria. Further work-up showed hypophosphatemia and hyperphosphaturia, hypouricemia and hyperuricosuria, and hyper aminoaciduria, consistent with Fanconi syndrome. A kidney biopsy was obtained and showed diffuse interstitial infiltrates with tubular necrosis. The patient improved after the initiation of a corticosteroid therapy, with tapering dose.

conclusionsWe reviewed the literature and found nine similar cases. This association mostly occurs in adult woman, without current evidence for an ethnic predilection, unlike previously reported. The renal prognosis seems favorable after corticosteroid therapy, even in case of severe renal injury. Nonetheless mild tubular defects may persist after treatment or spontaneous remission.

Indexed as

Fanconi SyndromeFemaleHumansMiddle AgedNephritis, InterstitialUveitisFanconi syndromeNephritis, interstitialTubulointerstitial nephritis and uveitisUveitis

Identifiers

PMID30340545
PMCPMC6194638
OpenAlexW2897771686

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.