Evidence map›Paper›PMID 30340405›Full record

ReviewSensors (Basel, Switzerland)2018

Silicon Photonic Biosensors Using Label-Free Detection.

Enxiao Luan, Hossam Shoman, Daniel M Ratner, Karen C Cheung, Lukas Chrostowski

Erratum issuedAbstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

  1. Article
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  17. Correction of 2Sensors (Basel, Switzerland) · 2024
    Article
  18. Article
  19. Review
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Enxiao LuanDepartment of Electrical and Computer Engineering, University of British Columbia, 2329 West Mall, Vancouver, BC V6T 1Z4, Canada. eluan@ece.ubc.ca.ORCID 0000-0001-6404-5433
Hossam ShomanDepartment of Electrical and Computer Engineering, University of British Columbia, 2329 West Mall, Vancouver, BC V6T 1Z4, Canada. hoshoman@ece.ubc.ca.
Daniel M RatnerDepartment of Bioengineering, University of Washington, 3720 15th Ave. NE, Seattle, WA 98195-5061, USA. dratner@uw.edu.
Karen C CheungDepartment of Electrical and Computer Engineering, University of British Columbia, 2329 West Mall, Vancouver, BC V6T 1Z4, Canada. kcheung@ece.ubc.ca.
Lukas ChrostowskiDepartment of Electrical and Computer Engineering, University of British Columbia, 2329 West Mall, Vancouver, BC V6T 1Z4, Canada. lukasc@ece.ubc.ca.

Funding

China Scholarship Council 201506120077
6 · The paper itself

Abstract

Thanks to advanced semiconductor microfabrication technology, chip-scale integration and miniaturization of lab-on-a-chip components, silicon-based optical biosensors have made significant progress for the purpose of point-of-care diagnosis. In this review, we provide an overview of the state-of-the-art in evanescent field biosensing technologies including interferometer, microcavity, photonic crystal, and Bragg grating waveguide-based sensors. Their sensing mechanisms and sensor performances, as well as real biomarkers for label-free detection, are exhibited and compared. We also review the development of chip-level integration for lab-on-a-chip photonic sensing platforms, which consist of the optical sensing device, flow delivery system, optical input and readout equipment. At last, some advanced system-level complementary metal-oxide semiconductor (CMOS) chip packaging examples are presented, indicating the commercialization potential for the low cost, high yield, portable biosensing platform leveraging CMOS processes.

Indexed as

Biosensing TechniquesEquipment DesignInterferometryLab-On-A-Chip DevicesMiniaturizationOptics and PhotonicsPhotonsSiliconSiliconBragg gratingevanescent optical field sensorlabel-free SOI biosensorlab-on-a-chipMach–Zehnder interferometermicrofluidicsphotonic crystalring resonatorsilicon photonicssub-wavelength grating

Identifiers

PMID30340405
PMCPMC6210424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.