Evidence map›Paper›PMID 30340377›Full record

ReviewVaccines2018

Memory T Cells in Flavivirus Vaccination.

Guangyu Li, Cody Teleki, Tian Wang

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Guangyu LiDepartment of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA. guli@UTMB.EDU.ORCID 0000-0002-7768-5584
Cody TelekiDepartment of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA. ccteleki@UTMB.EDU.ORCID 0000-0002-5922-1268
Tian WangDepartment of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA. ti1wang@utmb.edu.
The University of Texas Medical Branch at Galveston · US

Funding

Revolutionary Eilat-based Chikungunya Vaccine VectorR01AI127744 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WANG, TIAN · 2017 to 2021
$3.5M
Rational Development of Candidate Attenuated Flavivirus VaccinesR01AI099123 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WANG, TIAN · 2013 to 2016
$1.8M
National Institutes of Health R01 AI099123 , R01AI127744NIAID NIH HHS R01 AI099123NIAID NIH HHS R01 AI127744
6 · The paper itself

Abstract

Flaviviruses include many medically important viruses, such as Dengue virus (DENV), Japanese encephalitis (JEV), tick-borne encephalitis (TBEV), West Nile (WNV), yellow fever (YFV), and Zika viruses (ZIKV). Currently, there are licensed human vaccines for DENV, JEV, TBEV and YFV, but not for WNV or ZIKV. Memory T cells play a central role in adaptive immunity and are important for host protection during flavivirus infection. In this review, we discuss recent findings from animal models and clinical trials and provide new insights into the role of memory T cells in host protective immunity upon vaccination with the licensed flavivirus vaccines.

Indexed as

flavivirusmemory T cellsvaccine

Identifiers

PMID30340377
PMCPMC6313919
OpenAlexW2896864366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.