Evidence map›Paper›PMID 30340365›Full record

ArticleViruses2018

Ultrastructural Analysis of Chikungunya Virus Dissemination from the Midgut of the Yellow Fever Mosquito,

Asher M Kantor, DeAna G Grant, Velmurugan Balaraman, Tommi A White, Alexander W E Franz

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. The making of a dangerous vector: factors shaping the vector competence ofFrontiers in cellular and infection microbiology · 2025
    Review
  4. Article
  5. Article
  6. Cytoskeleton-associated gelsolin responds to the midgut distention process in saline meal-fed Aedes aegypti and affects arbovirus dissemination from the midgut.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Factors Affecting Arbovirus Midgut Escape in Mosquitoes.Pathogens (Basel, Switzerland) · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Asher M KantorDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA. amkt33@missouri.edu.
Velmurugan BalaramanDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA. balarama@vet.k-state.edu.ORCID 0000-0003-1671-5572
Tommi A White
Alexander W E FranzDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA. franza@missouri.edu.
University of Missouri · US

Funding

Arbovirus midgut escape mechanismsR01AI091972 · NIAID · KANSAS STATE UNIVERSITY · PI FRANZ, ALEXANDER W E, PASSARELLI, A. LORENA · 2012 to 2015
$2.6M
How Do Arboviruses Escape the Mosquito Midgut?- Analysis of a Novel MechanismR01AI134661 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI FRANZ, ALEXANDER W E · 2018 to 2022
$1.9M
NIAID NIH HHS R01 AI091972NIAID NIH HHS R01 AI134661
6 · The paper itself

Abstract

The transmission cycle of chikungunya virus (CHIKV) requires that mosquito vectors get persistently infected with the virus, following its oral acqsuisition from a vertebrate host. The mosquito midgut is the initial organ that gets infected with orally acquired CHIKV. Following its replication in the midgut epithelium, the virus exits the midgut and infects secondary tissues including the salivary glands before being transmitted to another host. Here, we investigate the pattern of CHIKV dissemination from the midgut of

Indexed as

AedesAnimalsBasement MembraneChikungunya virusFemaleGastrointestinal TractMicroscopy, Electron, TransmissionMosquito VectorsSalivary Glandsbasal laminabloodmealchikungunya virusdisseminationelectron microscopyFIB-SEMMayaro virusmidgutmosquitoultrastructural

Identifiers

PMID30340365
PMCPMC6213114
OpenAlexW2896170459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.