Trial reportPsychiatry research2018
Effects of post-exposure naps on exposure therapy for social anxiety.
Trial report in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Augmentation of Exposure Therapy for High Levels of Social Anxiety Using Post-exposure Naps
Mechanisms Underlying the Efficacy of Prolonged Exposure
Mechanisms Underlying Efficacy of Prolonged Exposure
Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- Using sleep to enhance exposure treatment for anxious children: A pilot study.The British journal of clinical psychology · 2026Trial
- Sleep quality and outcome of exposure therapy in adults with social anxiety disorder.Depression and anxiety · 2021Trial
- Sleep quality and treatment of social anxiety disorder.Anxiety, stress, and coping · 2019Trial
- The impact of exercise interventions on sleep in adult populations with depression, anxiety, or posttraumatic stress: review of the current evidence and future directions.Journal of behavioral medicine · 2025Review
- The effects of a dual orexin receptor antagonist on fear extinction memory and sleep in mice: Implications for exposure therapy.Behavioural brain research · 2024Article
- Article
- Comparison of autonomic reactivity to trauma and nightmare imagery: A Pilot Study.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Neurocognitive Model of Schema-Congruent and -Incongruent Learning in Clinical Disorders: Application to Social Anxiety and Beyond.Perspectives on psychological science : a journal of the Association for Psychological Science · 2023Article
- The Impact of Sleep on Fear Extinction.Current topics in behavioral neurosciences · 2023Article
- The influence of sleep on fear extinction in trauma-related disorders.Neurobiology of stress · 2023Article
- A transdiagnostic meta-analysis of acute augmentations to psychological therapy.Nature. Mental health · 2023Article
- Sleep's role in updating aversive autobiographical memories.Translational psychiatry · 2022Article
- Blocking the orexin system following therapeutic exposure promoted between session habituation, but not PTSD symptom reduction.Journal of psychiatric research · 2022Article
- Targeted Memory Reactivation During REM Sleep in Patients With Social Anxiety Disorder.Frontiers in psychiatry · 2022Article
- Altered sleep behavior in a genetic mouse model of impaired fear extinction.Scientific reports · 2021Article
- The role of sleep in fear learning and memory.Current opinion in psychology · 2020Review
- Fear in dreams and in wakefulness: Evidence for day/night affective homeostasis.Human brain mapping · 2020Article
- Sleep disturbance in PTSD and other anxiety-related disorders: an updated review of clinical features, physiological characteristics, and psychological and neurobiological mechanisms.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
Exposure therapy for social anxiety disorder (SAD) utilizes fear extinction, a memory process enhanced by sleep. We investigated whether naps following exposure sessions might improve symptoms and biomarkers in response to social stress in adults undergoing 5-week exposure-based group SAD therapy. Thirty-two participants aged 18-39 (18 females) with SAD were randomized. Before and after treatment, participants completed the Liebowitz Social Anxiety Scale (LSAS) and underwent a Trier Social Stress Test with psychophysiological monitoring (mpTSST) that included skin conductance (SCL), electromyographic (EMG) and electrocardiographic recording, and an auditory startle procedure while anticipating the social stressor. At sessions 3 and 4, exposure was followed by either a 120-min polysomnographically monitored sleep opportunity (Nap, N = 17) or wakefulness (Wake, N = 15). Primary hypotheses about SAD symptom change (LSAS) and EMG blink-startle response failed to differ with naps, despite significant symptom improvement (LSAS) with therapy. Some secondary biomarkers, however, provided preliminary support for enhanced extinction learning with naps, with trend-level Time (pre-, post-treatment) × Arm interactions and significant reduction from pre- to post treatment in the Nap arm alone for mpTSST SCL and salivary cortisol rise. Because of the small sample size and limited sleep duration, additional well-powered studies with more robust sleep interventions are indicated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.