Evidence map›Paper›PMID 30339778›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro.

Per Lundberg, Rune Andersson, Elizabeth S Machado, Tomaz Pinheiro da Costa, Cristina Barroso Hofer

Open access · goldAbstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Adverse Perinatal Outcomes among Adolescent Pregnant Women Living with HIV: A Propensity-Score-Matched Study.International journal of environmental research and public health · 2023
    Article
  3. Article
  4. Observational
  5. The next generation: Pregnancy in adolescents and women living with perinatally acquired HIV in South Africa.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Per LundbergGothenburg University, Sahlgrenska Academy, Institute of Biomedicine, Gothenburg, Sweden.
Rune AnderssonGothenburg University, Sahlgrenska Academy, Institute of Biomedicine, Gothenburg, Sweden.
Elizabeth S MachadoUniversidade Federal do Rio de Janeiro, Instituto de Puericultura e Pediatria Martagão Gesteira, Departmento de Medicina Preventiva, Rio de Janeiro, RJ, Brazil.
Tomaz Pinheiro da CostaUniversidade Federal do Rio de Janeiro, Instituto de Puericultura e Pediatria Martagão Gesteira, Departmento de Medicina Preventiva, Rio de Janeiro, RJ, Brazil.
Cristina Barroso HoferUniversidade Federal do Rio de Janeiro, Instituto de Puericultura e Pediatria Martagão Gesteira, Departmento de Medicina Preventiva, Rio de Janeiro, RJ, Brazil. Electronic address: cbhofer@hucff.ufrj.br.
Universidade Federal do Rio de Janeiro · BRUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerinatally HIV-infected children are surviving into adulthood, and getting pregnant. There is a scarcity of information on health and pregnancy outcomes in these women.

aimTo evaluate characteristics related to HIV disease and pregnancy outcomes in perinatally infected women, and to compare these women with a group of youth with behaviorally acquired HIV-infection, at a reference hospital in Rio de Janeiro, Brazil.

methodsA cohort study. Epidemiological, clinical, and laboratory data were compared between perinatally (PHIV) and behaviorally HIV-infected (BHIV) pregnant youth with the primary aim to study pregnancy outcomes in the PHIV group and compare with outcomes to BHIV group.

resultsThirty-two pregnancies occurred in PHIV group, and 595 in BHIV group. A total of seven (22%) PHIV women and 64 (11%) BHIV women had a premature delivery (p=0.04), however, when adjusting for younger age at pregnancy, and antiretroviral therapy initiation in 1st trimester of pregnancy (OR=18.66, 95%CI=5.52-63.14), the difference was no longer significant. No cases of mother-to-child HIV transmission (MTCT) were observed in the PHIV group while there was a 2% MTCT rate in BHIV group.

conclusionPregnancy among PHIV was as safe as among BHIV. The differences between those groups were probably related to treatment and prolonged care in the first group.

Indexed as

AdolescentAge FactorsAntiretroviral Therapy, Highly ActiveBrazilCD4 Lymphocyte CountFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalMultivariate AnalysisPregnancyPregnancy Complications, InfectiousPregnancy OutcomeProspective StudiesRisk FactorsUnsafe SexCombined antiretroviral treatmentMother-to-child transmissionPerinatal HIVPregnancy

Identifiers

PMID30339778
PMCPMC9427968
OpenAlexW2897046850

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.