Evidence map›Paper›PMID 30339682›Full record

ArticlePloS one2018

Two novel temperate bacteriophages infecting Streptococcus pyogenes: Their genomes, morphology and stability.

Marek Harhala, Jakub Barylski, Kinga Humińska-Lisowska, Dorota Lecion, Jacek Wojciechowicz, Karolina Lahutta, Marta Kuś, Andrew M Kropinski, Sylwia Nowak, Grzegorz Nowicki and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Survival Strategies ofViruses · 2021
    Article
  5. Article
  6. Article
  7. Phage therapy as a revolutionary medicine against Gram-positive bacterial infections.Beni-Suef University journal of basic and applied sciences · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Characterization of a Highly VirulentFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Marek HarhalaBacteriophage Laboratory, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, Wrocław, Poland.
Jakub BarylskiDepartment of Molecular Virology, Faculty of Biology, Adam Mickiewicz University, Collegium Biologicum-Umultowska 89, Poznan, Poland.
Kinga Humińska-LisowskaDNA Research Center, Inflancka 25, Poznań, Poland.
Dorota LecionBacteriophage Laboratory, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, Wrocław, Poland.
Jacek WojciechowiczDNA Research Center, Inflancka 25, Poznań, Poland.
Karolina LahuttaBacteriophage Laboratory, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, Wrocław, Poland.
Marta KuśDNA Research Center, Inflancka 25, Poznań, Poland.
Andrew M KropinskiDepartments of Pathobiology; and, Food Science, University of Guelph, Guelph, Ontario, Canada.
Sylwia NowakFaculty of Biological Sciences, Wrocław University, Kuznicza 35, Wrocław, Poland.
Grzegorz NowickiDepartment of Molecular Virology, Faculty of Biology, Adam Mickiewicz University, Collegium Biologicum-Umultowska 89, Poznan, Poland.
Katarzyna Hodyra-StefaniakBacteriophage Laboratory, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, Wrocław, Poland.
Krystyna DąbrowskaBacteriophage Laboratory, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, Wrocław, Poland.
Polish Academy of Sciences · PLAdam Mickiewicz University in Poznań · PLUniversity of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Only 3% of phage genomes in NCBI nucleotide database represent phages that are active against Streptococcus sp. With the aim to increase general awareness of phage diversity, we isolated two bacteriophages, Str01 and Str03, active against health-threatening Group A Streptococcus (GAS). Both phages are members of the Siphoviridae, but their analysis revealed that Str01 and Str03 do not belong to any known genus. We identified their structural proteins based on LC-ESI29 MS/MS and list their basic thermal stability and physico-chemical features including optimum pH. Annotated genomic sequences of the phages are deposited in GenBank (NCBI accession numbers KY349816 and KY363359, respectively).

Indexed as

Genome, ViralBacteriophagesGenes, ViralHydrogen-Ion ConcentrationMass SpectrometryPhylogenyStreptococcus pyogenesTemperatureViral ProteinsVirionViral Proteins

Identifiers

PMID30339682
PMCPMC6195288
OpenAlexW2896423264

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.