Evidence map›Paper›PMID 30339669›Full record

Trial reportPloS one2018

Regression techniques employing feature selection to predict clinical outcomes in stroke.

Yazan Abdel Majeed, Saria S Awadalla, James L Patton

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Key components of mechanical work predict outcomes in robotic stroke therapy.Journal of neuroengineering and rehabilitation · 2020
    Trial
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yazan Abdel MajeedArms and Hands Lab, Shirley Ryan Ability Lab, Chicago, IL, United States of America.ORCID 0000-0001-5401-1352
Saria S AwadallaEpidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL, United States of America.
James L PattonArms and Hands Lab, Shirley Ryan Ability Lab, Chicago, IL, United States of America.ORCID 0000-0001-7541-3561

Funding

Error-enhanced Learning & Recovery in 2 & 3 DimensionsR01NS053606 · NINDS · REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB · PI PATTON, JAMES LANPHIER · 2007 to 2024
$5.9M
NINDS NIH HHS R01 NS053606
6 · The paper itself

Abstract

It is not fully clear which measurable factors can reliably predict chronic stroke patients' recovery of motor ability. In this analysis, we investigate the impact of patient demographic characteristics, movement features, and a three-week upper-extremity intervention on the post-treatment change in two widely used clinical outcomes-the Upper Extremity portion of the Fugl-Meyer and the Wolf Motor Function Test. Models based on LASSO, which in validation tests account for 65% and 86% of the variability in Fugl-Meyer and Wolf, respectively, were used to identify the set of salient demographic and movement features. We found that age, affected limb, and several measures describing the patient's ability to efficiently direct motions with a single burst of speed were the most consequential in predicting clinical recovery. On the other hand, the upper-extremity intervention was not a significant predictor of recovery. Beyond a simple prognostic tool, these results suggest that focusing therapy on the more important features is likely to improve recovery. Such validation-intensive methods are a novel approach to determining the relative importance of patient-specific metrics and may help guide the design of customized therapy.

Indexed as

Recovery of FunctionStroke RehabilitationTelerehabilitationAge FactorsBiomechanical PhenomenaFemaleHumansMaleMiddle AgedMotor ActivityPrognosisRegression AnalysisSelf CareStrokeUpper Extremity

Identifiers

PMID30339669
PMCPMC6195279

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.