Evidence map›Paper›PMID 30339260›Full record

ArticleSocial cognitive and affective neuroscience2018

Temporal dynamics of spontaneous default-mode network activity mediate the association between reappraisal and depression.

Wei Gao, ShengDong Chen, Bharat Biswal, Xu Lei, JiaJin Yuan

Abstract read
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Article in Social cognitive and affective neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

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0cells of the map it votes in
11citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Wei GaoThe Laboratory for Affect Cognition and Regulation (ACRLAB), Key Laboratory of Cognition and Personality of Ministry of Education (SWU), Faculty of Psychology, Southwest University, Chongqing, China.
ShengDong ChenThe Laboratory for Affect Cognition and Regulation (ACRLAB), Key Laboratory of Cognition and Personality of Ministry of Education (SWU), Faculty of Psychology, Southwest University, Chongqing, China.
Bharat BiswalDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, USA.
Xu LeiSleep and Neuroimaging Center, Faculty of Psychology, Southwest University, Chongqing, China.
JiaJin YuanThe Laboratory for Affect Cognition and Regulation (ACRLAB), Key Laboratory of Cognition and Personality of Ministry of Education (SWU), Faculty of Psychology, Southwest University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive reappraisal is associated with major depressive disorder (MDD), while spontaneous activity patterns of the default mode network (DMN) is implicated in reappraisal and MDD. However, neural mechanisms subserving the close association of spontaneous reappraisal and depression are unclear. Spontaneous reappraisal, depression and resting-state functional magnetic resonance imaging (rsfMRI) were measured from 105 healthy subjects. We assessed the temporal complexity (Hurst exponent), Regional Homogeneity (ReHo) and fractional Amplitude of Low Frequency Fluctuation (fALFF) profiles of DMN, a network involved in both reappraisal and depression. Mediation effects of these standard measures on the relationship between reappraisal and depression, and the contributions of each DMN subregion, were assessed. Results indicated that Hurst exponent (H) of DMN, whether extracted by independent component analysis (ICA) or region of interest (ROI), was significantly associated with reappraisal scores. An individual with a higher reappraisal score has a lower Hurst value of DMN. Mediation analyses suggest that H of DMN partially mediates the association between reappraisal and the degree of depression, and this mediation effect arises from the contribution of medial prefrontal cortex. Neither ReHo nor fALFF showed a similar correlation or mediation effect. These findings suggest that temporal dynamics of DMN play an important role in emotion regulation and its association with depression. H of DMN may serve as a neural marker mediating the association between reappraisal and depression.

Indexed as

Brain MappingBrainDepressionEmotionsFemaleHumansMagnetic Resonance ImagingMajor Depressive DisorderPrefrontal CortexYoung Adult

Identifiers

PMID30339260
PMCPMC6277739

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.